The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

Button-Simons et al. report on two different genetic crosses of Plasmodium falciparum derived from Asian and African origin parasites, and generate large numbers of recombinant progeny. These crosses are characterized and have the potential to map biologically important traits across parasite genome...

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Autores principales: Katrina A. Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T. Haile, Catherine Jett, Lisa A. Checkley, Spencer Y. Kennedy, Richard S. Pinapati, Douglas A. Shoue, Marina McDew-White, Xue Li, François H. Nosten, Stefan H. Kappe, Timothy J. C. Anderson, Jeanne Romero-Severson, Michael T. Ferdig, Scott J. Emrich, Ashley M. Vaughan, Ian H. Cheeseman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/4b96c353972642afa3c35313f59f6b9c
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spelling oai:doaj.org-article:4b96c353972642afa3c35313f59f6b9c2021-12-02T16:04:30ZThe power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice10.1038/s42003-021-02210-12399-3642https://doaj.org/article/4b96c353972642afa3c35313f59f6b9c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02210-1https://doaj.org/toc/2399-3642Button-Simons et al. report on two different genetic crosses of Plasmodium falciparum derived from Asian and African origin parasites, and generate large numbers of recombinant progeny. These crosses are characterized and have the potential to map biologically important traits across parasite genomes.Katrina A. Button-SimonsSudhir KumarNelly CarmagoMeseret T. HaileCatherine JettLisa A. CheckleySpencer Y. KennedyRichard S. PinapatiDouglas A. ShoueMarina McDew-WhiteXue LiFrançois H. NostenStefan H. KappeTimothy J. C. AndersonJeanne Romero-SeversonMichael T. FerdigScott J. EmrichAshley M. VaughanIan H. CheesemanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Katrina A. Button-Simons
Sudhir Kumar
Nelly Carmago
Meseret T. Haile
Catherine Jett
Lisa A. Checkley
Spencer Y. Kennedy
Richard S. Pinapati
Douglas A. Shoue
Marina McDew-White
Xue Li
François H. Nosten
Stefan H. Kappe
Timothy J. C. Anderson
Jeanne Romero-Severson
Michael T. Ferdig
Scott J. Emrich
Ashley M. Vaughan
Ian H. Cheeseman
The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
description Button-Simons et al. report on two different genetic crosses of Plasmodium falciparum derived from Asian and African origin parasites, and generate large numbers of recombinant progeny. These crosses are characterized and have the potential to map biologically important traits across parasite genomes.
format article
author Katrina A. Button-Simons
Sudhir Kumar
Nelly Carmago
Meseret T. Haile
Catherine Jett
Lisa A. Checkley
Spencer Y. Kennedy
Richard S. Pinapati
Douglas A. Shoue
Marina McDew-White
Xue Li
François H. Nosten
Stefan H. Kappe
Timothy J. C. Anderson
Jeanne Romero-Severson
Michael T. Ferdig
Scott J. Emrich
Ashley M. Vaughan
Ian H. Cheeseman
author_facet Katrina A. Button-Simons
Sudhir Kumar
Nelly Carmago
Meseret T. Haile
Catherine Jett
Lisa A. Checkley
Spencer Y. Kennedy
Richard S. Pinapati
Douglas A. Shoue
Marina McDew-White
Xue Li
François H. Nosten
Stefan H. Kappe
Timothy J. C. Anderson
Jeanne Romero-Severson
Michael T. Ferdig
Scott J. Emrich
Ashley M. Vaughan
Ian H. Cheeseman
author_sort Katrina A. Button-Simons
title The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
title_short The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
title_full The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
title_fullStr The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
title_full_unstemmed The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
title_sort power and promise of genetic mapping from plasmodium falciparum crosses utilizing human liver-chimeric mice
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4b96c353972642afa3c35313f59f6b9c
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