Ensa controls S-phase length by modulating Treslin levels

The Greatwall/Ensa/PP2A-B55 pathway controls mitotic substrate phosphorylation and mitotic entry. Here the authors show that cells regulate S phase duration by controlling the ubiquitin-proteasome degradation of Treslin in a Gwl/Ensa-dependent pathway.

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Autores principales: Sophie Charrasse, Aicha Gharbi-Ayachi, Andrew Burgess, Jorge Vera, Khaled Hached, Peggy Raynaud, Etienne Schwob, Thierry Lorca, Anna Castro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4b97b11010a7439ab7bbf5e1c7ec312e
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spelling oai:doaj.org-article:4b97b11010a7439ab7bbf5e1c7ec312e2021-12-02T14:16:47ZEnsa controls S-phase length by modulating Treslin levels10.1038/s41467-017-00339-42041-1723https://doaj.org/article/4b97b11010a7439ab7bbf5e1c7ec312e2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00339-4https://doaj.org/toc/2041-1723The Greatwall/Ensa/PP2A-B55 pathway controls mitotic substrate phosphorylation and mitotic entry. Here the authors show that cells regulate S phase duration by controlling the ubiquitin-proteasome degradation of Treslin in a Gwl/Ensa-dependent pathway.Sophie CharrasseAicha Gharbi-AyachiAndrew BurgessJorge VeraKhaled HachedPeggy RaynaudEtienne SchwobThierry LorcaAnna CastroNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sophie Charrasse
Aicha Gharbi-Ayachi
Andrew Burgess
Jorge Vera
Khaled Hached
Peggy Raynaud
Etienne Schwob
Thierry Lorca
Anna Castro
Ensa controls S-phase length by modulating Treslin levels
description The Greatwall/Ensa/PP2A-B55 pathway controls mitotic substrate phosphorylation and mitotic entry. Here the authors show that cells regulate S phase duration by controlling the ubiquitin-proteasome degradation of Treslin in a Gwl/Ensa-dependent pathway.
format article
author Sophie Charrasse
Aicha Gharbi-Ayachi
Andrew Burgess
Jorge Vera
Khaled Hached
Peggy Raynaud
Etienne Schwob
Thierry Lorca
Anna Castro
author_facet Sophie Charrasse
Aicha Gharbi-Ayachi
Andrew Burgess
Jorge Vera
Khaled Hached
Peggy Raynaud
Etienne Schwob
Thierry Lorca
Anna Castro
author_sort Sophie Charrasse
title Ensa controls S-phase length by modulating Treslin levels
title_short Ensa controls S-phase length by modulating Treslin levels
title_full Ensa controls S-phase length by modulating Treslin levels
title_fullStr Ensa controls S-phase length by modulating Treslin levels
title_full_unstemmed Ensa controls S-phase length by modulating Treslin levels
title_sort ensa controls s-phase length by modulating treslin levels
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4b97b11010a7439ab7bbf5e1c7ec312e
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