Ensa controls S-phase length by modulating Treslin levels

Ensa controls S-phase length by modulating Treslin levels

The Greatwall/Ensa/PP2A-B55 pathway controls mitotic substrate phosphorylation and mitotic entry. Here the authors show that cells regulate S phase duration by controlling the ubiquitin-proteasome degradation of Treslin in a Gwl/Ensa-dependent pathway.

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Autores principales: Sophie Charrasse, Aicha Gharbi-Ayachi, Andrew Burgess, Jorge Vera, Khaled Hached, Peggy Raynaud, Etienne Schwob, Thierry Lorca, Anna Castro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/4b97b11010a7439ab7bbf5e1c7ec312e
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