Myelin replacement triggered by single-cell demyelination in mouse cortex

Myelination is a highly regulated phenomenon. Here, the authors show that demyelination induced by the loss of a single oligodendrocyte triggers replenishment of a specific fraction the original myelin and myelination of previously unmyelinated axons in the mouse cortex.

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Autores principales:	Nicolas Snaidero, Martina Schifferer, Aleksandra Mezydlo, Bernard Zalc, Martin Kerschensteiner, Thomas Misgeld
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ba34fe403224d65a930fcc6e780b038
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spelling	oai:doaj.org-article:4ba34fe403224d65a930fcc6e780b0382021-12-02T18:51:37ZMyelin replacement triggered by single-cell demyelination in mouse cortex10.1038/s41467-020-18632-02041-1723https://doaj.org/article/4ba34fe403224d65a930fcc6e780b0382020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18632-0https://doaj.org/toc/2041-1723Myelination is a highly regulated phenomenon. Here, the authors show that demyelination induced by the loss of a single oligodendrocyte triggers replenishment of a specific fraction the original myelin and myelination of previously unmyelinated axons in the mouse cortex.Nicolas SnaideroMartina SchiffererAleksandra MezydloBernard ZalcMartin KerschensteinerThomas MisgeldNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicolas Snaidero Martina Schifferer Aleksandra Mezydlo Bernard Zalc Martin Kerschensteiner Thomas Misgeld Myelin replacement triggered by single-cell demyelination in mouse cortex
description	Myelination is a highly regulated phenomenon. Here, the authors show that demyelination induced by the loss of a single oligodendrocyte triggers replenishment of a specific fraction the original myelin and myelination of previously unmyelinated axons in the mouse cortex.
format	article
author	Nicolas Snaidero Martina Schifferer Aleksandra Mezydlo Bernard Zalc Martin Kerschensteiner Thomas Misgeld
author_facet	Nicolas Snaidero Martina Schifferer Aleksandra Mezydlo Bernard Zalc Martin Kerschensteiner Thomas Misgeld
author_sort	Nicolas Snaidero
title	Myelin replacement triggered by single-cell demyelination in mouse cortex
title_short	Myelin replacement triggered by single-cell demyelination in mouse cortex
title_full	Myelin replacement triggered by single-cell demyelination in mouse cortex
title_fullStr	Myelin replacement triggered by single-cell demyelination in mouse cortex
title_full_unstemmed	Myelin replacement triggered by single-cell demyelination in mouse cortex
title_sort	myelin replacement triggered by single-cell demyelination in mouse cortex
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4ba34fe403224d65a930fcc6e780b038
work_keys_str_mv	AT nicolassnaidero myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex AT martinaschifferer myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex AT aleksandramezydlo myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex AT bernardzalc myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex AT martinkerschensteiner myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex AT thomasmisgeld myelinreplacementtriggeredbysinglecelldemyelinationinmousecortex
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Myelin replacement triggered by single-cell demyelination in mouse cortex

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