Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.
Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, Nrp1 null embryos display vascular defects that differ from those of mice lacking either VEGF-A164 or Sema3A proteins. Furthermore, it has been rec...
Saved in:
Main Authors: | Donatella Valdembri, Patrick T Caswell, Kurt I Anderson, Juliane P Schwarz, Ireen König, Elena Astanina, Francesca Caccavari, Jim C Norman, Martin J Humphries, Federico Bussolino, Guido Serini |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
|
Subjects: | |
Online Access: | https://doaj.org/article/4ba63edc09624beebbe0aa89b3203a1c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis
by: Giulia Mana, et al.
Published: (2016) -
Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis
by: Sneha Vivekanandhan, et al.
Published: (2017) -
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution
by: Christina M. Termini, et al.
Published: (2021) -
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity
by: Roberto Diaz-Marin, et al.
Published: (2021) -
Neuropilin-1 Regulates the Secondary CD8 T Cell Response to Virus Infection
by: Ji Young Hwang, et al.
Published: (2019)