Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.

<h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodolo...

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Autores principales: Yu-Tzu Wu, Hsin-Yi Lee, Samuel Norton, Chuanfeng Chen, Hongxia Chen, Chenglin He, Jane Fleming, Fiona E Matthews, Carol Brayne
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Publicado: Public Library of Science (PLoS) 2013
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spelling oai:doaj.org-article:4ba8f185e27f4f81aaa9d945856b9e282021-11-18T07:42:13ZPrevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.1932-620310.1371/journal.pone.0066252https://doaj.org/article/4ba8f185e27f4f81aaa9d945856b9e282013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776645/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodological factors with the aim of producing estimates of the numbers of people with dementia in these areas.<h4>Method and findings</h4>A search of Chinese and English databases identified 76 dementia prevalence studies based on samples drawn from mainland China, Hong Kong and Taiwan between 1980 and 2012. A pattern of significantly decreasing prevalence was observed from northern, central, southern areas of mainland China, Hong Kong and Taiwan. Area variations in dementia prevalence were not explained by differences in methodological factors (diagnostic criteria, age range, study sample size and sampling method), socioeconomic level or life expectancy between areas. The results of meta-analysis were applied to current population data to provide best estimate. Based on the DSM-IV diagnostic criteria, the total number of people aged 60 and over with dementia in mainland China, Hong Kong and Taiwan is 8.4 million (4.6%, 95% CI: 3.4, 5.8) and in northern, central and southern areas are 3.8 (5.1%, 95% CI: 4.1, 6.1), 3.2 (4.4%, 95% CI: 3.2, 5.6) and 1.2 (3.9%, 95% CI: 2.3, 5.4) million respectively. These estimates were mainly based on the studies existing in highly developed areas and potentially affected by incomplete and insufficient data.<h4>Conclusions</h4>The findings of this review provide a robust estimate of area differences in dementia prevalence. Application of the estimated prevalence to population data reveals the number of people with dementia is expected to double every 20 years, areas in mainland China will be facing the greatest dementia challenge.Yu-Tzu WuHsin-Yi LeeSamuel NortonChuanfeng ChenHongxia ChenChenglin HeJane FlemingFiona E MatthewsCarol BraynePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 6, p e66252 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Yu-Tzu Wu
Hsin-Yi Lee
Samuel Norton
Chuanfeng Chen
Hongxia Chen
Chenglin He
Jane Fleming
Fiona E Matthews
Carol Brayne
Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
description <h4>Background</h4>Many studies have considered the prevalence of dementia in mainland China, Hong Kong and Taiwan. However, area level estimates have not been produced. This study examines area differences across mainland China, Hong Kong and Taiwan adjusting for the effect of methodological factors with the aim of producing estimates of the numbers of people with dementia in these areas.<h4>Method and findings</h4>A search of Chinese and English databases identified 76 dementia prevalence studies based on samples drawn from mainland China, Hong Kong and Taiwan between 1980 and 2012. A pattern of significantly decreasing prevalence was observed from northern, central, southern areas of mainland China, Hong Kong and Taiwan. Area variations in dementia prevalence were not explained by differences in methodological factors (diagnostic criteria, age range, study sample size and sampling method), socioeconomic level or life expectancy between areas. The results of meta-analysis were applied to current population data to provide best estimate. Based on the DSM-IV diagnostic criteria, the total number of people aged 60 and over with dementia in mainland China, Hong Kong and Taiwan is 8.4 million (4.6%, 95% CI: 3.4, 5.8) and in northern, central and southern areas are 3.8 (5.1%, 95% CI: 4.1, 6.1), 3.2 (4.4%, 95% CI: 3.2, 5.6) and 1.2 (3.9%, 95% CI: 2.3, 5.4) million respectively. These estimates were mainly based on the studies existing in highly developed areas and potentially affected by incomplete and insufficient data.<h4>Conclusions</h4>The findings of this review provide a robust estimate of area differences in dementia prevalence. Application of the estimated prevalence to population data reveals the number of people with dementia is expected to double every 20 years, areas in mainland China will be facing the greatest dementia challenge.
format article
author Yu-Tzu Wu
Hsin-Yi Lee
Samuel Norton
Chuanfeng Chen
Hongxia Chen
Chenglin He
Jane Fleming
Fiona E Matthews
Carol Brayne
author_facet Yu-Tzu Wu
Hsin-Yi Lee
Samuel Norton
Chuanfeng Chen
Hongxia Chen
Chenglin He
Jane Fleming
Fiona E Matthews
Carol Brayne
author_sort Yu-Tzu Wu
title Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
title_short Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
title_full Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
title_fullStr Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
title_full_unstemmed Prevalence studies of dementia in mainland china, Hong Kong and taiwan: a systematic review and meta-analysis.
title_sort prevalence studies of dementia in mainland china, hong kong and taiwan: a systematic review and meta-analysis.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/4ba8f185e27f4f81aaa9d945856b9e28
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