Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

Both intrinsic and external signals regulate stem cell fate. Here, the authors perform a genome-wide RNAi screen to identify regulators of testis germline stem cells (GSC) in Drosophila, finding more than half of the genes were external regulators and heterochromatin/cytokinesis proteins mediated GS...

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Autores principales:	Ying Liu, Qinglan Ge, Brian Chan, Hanhan Liu, Shree Ram Singh, Jacob Manley, Jae Lee, Ann Marie Weideman, Gerald Hou, Steven X. Hou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4bacdc24e3e94f74b5fe7c8b9d8f0369
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spelling	oai:doaj.org-article:4bacdc24e3e94f74b5fe7c8b9d8f03692021-12-02T14:39:15ZWhole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila10.1038/ncomms121492041-1723https://doaj.org/article/4bacdc24e3e94f74b5fe7c8b9d8f03692016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12149https://doaj.org/toc/2041-1723Both intrinsic and external signals regulate stem cell fate. Here, the authors perform a genome-wide RNAi screen to identify regulators of testis germline stem cells (GSC) in Drosophila, finding more than half of the genes were external regulators and heterochromatin/cytokinesis proteins mediated GSC fate.Ying LiuQinglan GeBrian ChanHanhan LiuShree Ram SinghJacob ManleyJae LeeAnn Marie WeidemanGerald HouSteven X. HouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ying Liu Qinglan Ge Brian Chan Hanhan Liu Shree Ram Singh Jacob Manley Jae Lee Ann Marie Weideman Gerald Hou Steven X. Hou Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
description	Both intrinsic and external signals regulate stem cell fate. Here, the authors perform a genome-wide RNAi screen to identify regulators of testis germline stem cells (GSC) in Drosophila, finding more than half of the genes were external regulators and heterochromatin/cytokinesis proteins mediated GSC fate.
format	article
author	Ying Liu Qinglan Ge Brian Chan Hanhan Liu Shree Ram Singh Jacob Manley Jae Lee Ann Marie Weideman Gerald Hou Steven X. Hou
author_facet	Ying Liu Qinglan Ge Brian Chan Hanhan Liu Shree Ram Singh Jacob Manley Jae Lee Ann Marie Weideman Gerald Hou Steven X. Hou
author_sort	Ying Liu
title	Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
title_short	Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
title_full	Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
title_fullStr	Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
title_full_unstemmed	Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
title_sort	whole-animal genome-wide rnai screen identifies networks regulating male germline stem cells in drosophila
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4bacdc24e3e94f74b5fe7c8b9d8f0369
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Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

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