VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta.
Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA and chondroitin sulphate-A (CSA) receptor. Polymorphisms in these domains, including DBL2X and DBL3X, may affect their antig...
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Autores principales: | Eduard Rovira-Vallbona, Isadora Monteiro, Azucena Bardají, Elisa Serra-Casas, Daniel E Neafsey, Diana Quelhas, Clarissa Valim, Pedro Alonso, Carlota Dobaño, Jaume Ordi, Clara Menéndez, Alfredo Mayor |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/4bb28a11c9f74b0ca9228dadef771ec6 |
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