VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta.

VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta.

Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA and chondroitin sulphate-A (CSA) receptor. Polymorphisms in these domains, including DBL2X and DBL3X, may affect their antig...

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Main Authors: Eduard Rovira-Vallbona, Isadora Monteiro, Azucena Bardají, Elisa Serra-Casas, Daniel E Neafsey, Diana Quelhas, Clarissa Valim, Pedro Alonso, Carlota Dobaño, Jaume Ordi, Clara Menéndez, Alfredo Mayor
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/4bb28a11c9f74b0ca9228dadef771ec6
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https://doaj.org/article/4bb28a11c9f74b0ca9228dadef771ec6

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