Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography

Nauman Hashmani, Maria Hashmani, Noureen Asghar, Mahnoor Islam, Sharif Hashmani Department of Ophthalmology and Visual Sciences, Hashmanis Hospital, Karachi, PakistanCorrespondence: Nauman Hashmani 68/B Khayaban-e-Shahbaz, DHA Phase 7, Karachi, PakistanTel +92 321-2828062Email naumanhashmani@hashman...

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Autores principales:	Hashmani N, Hashmani M, Asghar N, Islam M, Hashmani S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	cornea corneal stroma oct as-oct tomography topography Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/4bb642accf9c49c2953588657d131ff2
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spelling	oai:doaj.org-article:4bb642accf9c49c2953588657d131ff22021-12-02T08:41:27ZWide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography1177-5483https://doaj.org/article/4bb642accf9c49c2953588657d131ff22020-03-01T00:00:00Zhttps://www.dovepress.com/wide-stromal-mapping-using-an-anterior-segment-optical-coherence-tomog-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Nauman Hashmani, Maria Hashmani, Noureen Asghar, Mahnoor Islam, Sharif Hashmani Department of Ophthalmology and Visual Sciences, Hashmanis Hospital, Karachi, PakistanCorrespondence: Nauman Hashmani 68/B Khayaban-e-Shahbaz, DHA Phase 7, Karachi, PakistanTel +92 321-2828062Email naumanhashmani@hashmanis.edu.pkPurpose: To quantify and assess the reproducibility of the corneal stromal thickness profiles captured by the SD-OCT. Secondly, we correlated the zonal thicknesses to the age, gender and axial length.Methods: We included 227 normal eyes of 227 patients with a maximum hypermetropia of +5 and myopia of – 6 diopters (D). Subjects with an intraocular pressure exceeding 22 mm Hg, evidence of cataract formation, history of ophthalmic surgery or disease were excluded. Lastly, reproducibility was evaluated in a subset of 50 participants by means of an identical scan protocol repeated by 2 different OCT operators.Results: Stromal values were consistently thicker in the peripheral cornea (p< 0.001). Age was negatively correlated with approximately every sector of the stroma with notable exceptions of the center (r=0.117, p=0.088) and the superior inner (r=0.057, 0.409), middle (r=0.086, p=0.209) and outer locations (r=0.120, p=0.079). There was no statistical significance in most sectors when looking at the axial length, gender and K1/K2. This method was highly reproducible in terms of both the ICC and COV.Conclusion: Corneal stromal mapping is highly reproducible and shows a negative correlation to age. Additionally, the periphery of the stroma is consistently thicker to the center. Other variables like gender and axial length show no relationship to the corneal stroma.Keywords: cornea, corneal stroma, OCT, AS-OCT, tomography, topographyHashmani NHashmani MAsghar NIslam MHashmani SDove Medical Pressarticlecorneacorneal stromaoctas-octtomographytopographyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 751-757 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cornea corneal stroma oct as-oct tomography topography Ophthalmology RE1-994
spellingShingle	cornea corneal stroma oct as-oct tomography topography Ophthalmology RE1-994 Hashmani N Hashmani M Asghar N Islam M Hashmani S Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
description	Nauman Hashmani, Maria Hashmani, Noureen Asghar, Mahnoor Islam, Sharif Hashmani Department of Ophthalmology and Visual Sciences, Hashmanis Hospital, Karachi, PakistanCorrespondence: Nauman Hashmani 68/B Khayaban-e-Shahbaz, DHA Phase 7, Karachi, PakistanTel +92 321-2828062Email naumanhashmani@hashmanis.edu.pkPurpose: To quantify and assess the reproducibility of the corneal stromal thickness profiles captured by the SD-OCT. Secondly, we correlated the zonal thicknesses to the age, gender and axial length.Methods: We included 227 normal eyes of 227 patients with a maximum hypermetropia of +5 and myopia of – 6 diopters (D). Subjects with an intraocular pressure exceeding 22 mm Hg, evidence of cataract formation, history of ophthalmic surgery or disease were excluded. Lastly, reproducibility was evaluated in a subset of 50 participants by means of an identical scan protocol repeated by 2 different OCT operators.Results: Stromal values were consistently thicker in the peripheral cornea (p< 0.001). Age was negatively correlated with approximately every sector of the stroma with notable exceptions of the center (r=0.117, p=0.088) and the superior inner (r=0.057, 0.409), middle (r=0.086, p=0.209) and outer locations (r=0.120, p=0.079). There was no statistical significance in most sectors when looking at the axial length, gender and K1/K2. This method was highly reproducible in terms of both the ICC and COV.Conclusion: Corneal stromal mapping is highly reproducible and shows a negative correlation to age. Additionally, the periphery of the stroma is consistently thicker to the center. Other variables like gender and axial length show no relationship to the corneal stroma.Keywords: cornea, corneal stroma, OCT, AS-OCT, tomography, topography
format	article
author	Hashmani N Hashmani M Asghar N Islam M Hashmani S
author_facet	Hashmani N Hashmani M Asghar N Islam M Hashmani S
author_sort	Hashmani N
title	Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
title_short	Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
title_full	Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
title_fullStr	Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
title_full_unstemmed	Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography
title_sort	wide stromal mapping using an anterior segment optical coherence tomography
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/4bb642accf9c49c2953588657d131ff2
work_keys_str_mv	AT hashmanin widestromalmappingusingananteriorsegmentopticalcoherencetomography AT hashmanim widestromalmappingusingananteriorsegmentopticalcoherencetomography AT asgharn widestromalmappingusingananteriorsegmentopticalcoherencetomography AT islamm widestromalmappingusingananteriorsegmentopticalcoherencetomography AT hashmanis widestromalmappingusingananteriorsegmentopticalcoherencetomography
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Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography

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