The development of the posterity of male and female outbred rats exposed to sublimate

Mercury has gonadotropic and mutagenic effects on the Mammalia organism. This fact indicates the possibility of appearance of the mercury exposure effects on the offspring whose parents were exposed to this toxicant. The sublimate effects on the development of the first generation offspring from mal...

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Autor principal:	E. A. Kapustina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	albino rats posterity sublimate development Science Q
Acceso en línea:	https://doaj.org/article/4bb66290b6ff406c8403c5b1b15ecda1
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spelling	oai:doaj.org-article:4bb66290b6ff406c8403c5b1b15ecda12021-11-23T06:14:26ZThe development of the posterity of male and female outbred rats exposed to sublimate2541-94202587-9596https://doaj.org/article/4bb66290b6ff406c8403c5b1b15ecda12013-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1413https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Mercury has gonadotropic and mutagenic effects on the Mammalia organism. This fact indicates the possibility of appearance of the mercury exposure effects on the offspring whose parents were exposed to this toxicant. The sublimate effects on the development of the first generation offspring from male and female outbred rats exposed to this substance were studied. Sublimate solution. (0,05 mg of mercury for 100 g of animal's body weight) was injected subcutaneously to outbred rats during 6 weeks. After ending of the injections these rats were mated with intact rats for getting the posterity. The examination of albino rats posterity had two stages. The first stage was to study the development of sensor-motional reactions on the first and. the tenth days of life. The second stage included the research of zoosocial behavior of sexually mature rats and. their activity in open field. Also the posterity was weighted for estimation of physical development. Obtained, materials of the researches were elaborated with use of methods of nonparametric statistics (Mann — Whitney U-criteria). At the analysis of the results of the experiment we revealed statistically significant differences in body weight and. motive activity of animals of experimental group in comparison with control group. Decrease of body weight in posterity of experimental male rats was revealed and. there were no differences in maturation of sensor-motional reflexes in their first days of life. Increase of body weight and motional activity was revealed in posterity of female rats with sublimate intoxication in comparison with control values. Changes of body weight and. behavior were registered in sexually mature posterity. Increase of body weight in comparison with control group was registered at the weighing of experimental animals. Depression of motive, position-finding, research and zoosocial activity was revealed in posterity of experimental male rats. Depression of motive, position-finding and. research activity was revealed in male posterity of experimental female rats and. strengthening of position-finding and. research activity was revealed in their female posterity.E. A. KapustinaScientific Сentre for Family Health and Human Reproduction Problemsarticlealbino ratsposteritysublimatedevelopmentScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 102-105 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	albino rats posterity sublimate development Science Q
spellingShingle	albino rats posterity sublimate development Science Q E. A. Kapustina The development of the posterity of male and female outbred rats exposed to sublimate
description	Mercury has gonadotropic and mutagenic effects on the Mammalia organism. This fact indicates the possibility of appearance of the mercury exposure effects on the offspring whose parents were exposed to this toxicant. The sublimate effects on the development of the first generation offspring from male and female outbred rats exposed to this substance were studied. Sublimate solution. (0,05 mg of mercury for 100 g of animal's body weight) was injected subcutaneously to outbred rats during 6 weeks. After ending of the injections these rats were mated with intact rats for getting the posterity. The examination of albino rats posterity had two stages. The first stage was to study the development of sensor-motional reactions on the first and. the tenth days of life. The second stage included the research of zoosocial behavior of sexually mature rats and. their activity in open field. Also the posterity was weighted for estimation of physical development. Obtained, materials of the researches were elaborated with use of methods of nonparametric statistics (Mann — Whitney U-criteria). At the analysis of the results of the experiment we revealed statistically significant differences in body weight and. motive activity of animals of experimental group in comparison with control group. Decrease of body weight in posterity of experimental male rats was revealed and. there were no differences in maturation of sensor-motional reflexes in their first days of life. Increase of body weight and motional activity was revealed in posterity of female rats with sublimate intoxication in comparison with control values. Changes of body weight and. behavior were registered in sexually mature posterity. Increase of body weight in comparison with control group was registered at the weighing of experimental animals. Depression of motive, position-finding, research and zoosocial activity was revealed in posterity of experimental male rats. Depression of motive, position-finding and. research activity was revealed in male posterity of experimental female rats and. strengthening of position-finding and. research activity was revealed in their female posterity.
format	article
author	E. A. Kapustina
author_facet	E. A. Kapustina
author_sort	E. A. Kapustina
title	The development of the posterity of male and female outbred rats exposed to sublimate
title_short	The development of the posterity of male and female outbred rats exposed to sublimate
title_full	The development of the posterity of male and female outbred rats exposed to sublimate
title_fullStr	The development of the posterity of male and female outbred rats exposed to sublimate
title_full_unstemmed	The development of the posterity of male and female outbred rats exposed to sublimate
title_sort	development of the posterity of male and female outbred rats exposed to sublimate
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/4bb66290b6ff406c8403c5b1b15ecda1
work_keys_str_mv	AT eakapustina thedevelopmentoftheposterityofmaleandfemaleoutbredratsexposedtosublimate AT eakapustina developmentoftheposterityofmaleandfemaleoutbredratsexposedtosublimate
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The development of the posterity of male and female outbred rats exposed to sublimate

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