The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles

Abstract Selfish genetic elements have been found in the genomes of many species, yet our understanding of their evolutionary dynamics is only partially understood. A number of distinct selfish Medea elements are naturally present in many populations of the red flour beetle (Tribolium castaneum). Al...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sarah A. Cash, Michael A. Robert, Marcé D. Lorenzen, Fred Gould
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2020
Materias:	gene drive maternal effect Medea selfish genetic element Ecology QH540-549.5
Acceso en línea:	https://doaj.org/article/4bba5c23d0a24a4f8cd64d5516a05843
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4bba5c23d0a24a4f8cd64d5516a05843
record_format	dspace
spelling	oai:doaj.org-article:4bba5c23d0a24a4f8cd64d5516a058432021-11-04T13:06:09ZThe impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles2045-775810.1002/ece3.5946https://doaj.org/article/4bba5c23d0a24a4f8cd64d5516a058432020-01-01T00:00:00Zhttps://doi.org/10.1002/ece3.5946https://doaj.org/toc/2045-7758Abstract Selfish genetic elements have been found in the genomes of many species, yet our understanding of their evolutionary dynamics is only partially understood. A number of distinct selfish Medea elements are naturally present in many populations of the red flour beetle (Tribolium castaneum). Although these Medea elements are predicted by models to increase in frequency within populations because any offspring of a Medea‐bearing mother that do not inherit at least one Medea allele will die, experiments demonstrating an increase in a naturally occurring Medea element are lacking. Our survey of the specific Medea element, M1, in the United States showed that it had a patchy geographic distribution. From the survey, it could not be determined if this distribution was caused by a slow process of M1 colonization of discrete populations or if some populations lacked M1 because they had genetic factors conferring resistance to the Medea mechanism. We show that populations with naturally low to intermediate M1 frequencies likely represent transient states during the process of Medea spread. Furthermore, we find no evidence that genetic factors are excluding M1 from US populations where the element is not presently found. We also show how a known suppressor of Medea can impair the increase of M1 in populations and discuss the implications of our findings for pest‐management applications of Medea elements.Sarah A. CashMichael A. RobertMarcé D. LorenzenFred GouldWileyarticlegene drivematernal effectMedeaselfish genetic elementEcologyQH540-549.5ENEcology and Evolution, Vol 10, Iss 2, Pp 863-874 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	gene drive maternal effect Medea selfish genetic element Ecology QH540-549.5
spellingShingle	gene drive maternal effect Medea selfish genetic element Ecology QH540-549.5 Sarah A. Cash Michael A. Robert Marcé D. Lorenzen Fred Gould The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
description	Abstract Selfish genetic elements have been found in the genomes of many species, yet our understanding of their evolutionary dynamics is only partially understood. A number of distinct selfish Medea elements are naturally present in many populations of the red flour beetle (Tribolium castaneum). Although these Medea elements are predicted by models to increase in frequency within populations because any offspring of a Medea‐bearing mother that do not inherit at least one Medea allele will die, experiments demonstrating an increase in a naturally occurring Medea element are lacking. Our survey of the specific Medea element, M1, in the United States showed that it had a patchy geographic distribution. From the survey, it could not be determined if this distribution was caused by a slow process of M1 colonization of discrete populations or if some populations lacked M1 because they had genetic factors conferring resistance to the Medea mechanism. We show that populations with naturally low to intermediate M1 frequencies likely represent transient states during the process of Medea spread. Furthermore, we find no evidence that genetic factors are excluding M1 from US populations where the element is not presently found. We also show how a known suppressor of Medea can impair the increase of M1 in populations and discuss the implications of our findings for pest‐management applications of Medea elements.
format	article
author	Sarah A. Cash Michael A. Robert Marcé D. Lorenzen Fred Gould
author_facet	Sarah A. Cash Michael A. Robert Marcé D. Lorenzen Fred Gould
author_sort	Sarah A. Cash
title	The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
title_short	The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
title_full	The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
title_fullStr	The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
title_full_unstemmed	The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles
title_sort	impact of local population genetic background on the spread of the selfish element medea‐1 in red flour beetles
publisher	Wiley
publishDate	2020
url	https://doaj.org/article/4bba5c23d0a24a4f8cd64d5516a05843
work_keys_str_mv	AT sarahacash theimpactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT michaelarobert theimpactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT marcedlorenzen theimpactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT fredgould theimpactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT sarahacash impactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT michaelarobert impactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT marcedlorenzen impactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles AT fredgould impactoflocalpopulationgeneticbackgroundonthespreadoftheselfishelementmedea1inredflourbeetles
_version_	1718444898411085824

The impact of local population genetic background on the spread of the selfish element Medea‐1 in red flour beetles

Ejemplares similares