Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

ABSTRACT Broadly neutralizing antibodies that recognize the conserved hemagglutinin (HA) stalk have emerged as exciting new biotherapeutic tools to combat seasonal and pandemic influenza viruses. Our general understanding of the mechanisms by which stalk-specific antibodies achieve protection is rap...

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Main Authors: Caitlin E. Mullarkey, Mark J. Bailey, Diana A. Golubeva, Gene S. Tan, Raffael Nachbagauer, Wenqian He, Kyle E. Novakowski, Dawn M. Bowdish, Matthew S. Miller, Peter Palese
Format: article
Language:EN
Published: American Society for Microbiology 2016
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Online Access:https://doaj.org/article/4bbce642e91f4976b1eb4fb477618082
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