Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet.
There is growing evidence that mitochondrial dysfunction, and more specifically fatty acid β-oxidation impairment, is involved in the pathophysiology of non-alcoholic steatohepatitis (NASH). The goal of the present study was to achieve more understanding on the modification/s of carnitinepalmitoyltr...
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Auteurs principaux: | Gaetano Serviddio, Anna M Giudetti, Francesco Bellanti, Paola Priore, Tiziana Rollo, Rosanna Tamborra, Luisa Siculella, Gianluigi Vendemiale, Emanuele Altomare, Gabriele V Gnoni |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/4bbd3c3dfb5a4b44b0932b8fbc5f91f4 |
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