Common cortical areas have different neural mechanisms for covert and overt visual pursuits

Abstract Although humans can direct their attention to visual targets with or without eye movements, it remains unclear how different brain mechanisms control visual attention and eye movements together and/or separately. Here, we measured MEG and fMRI data during covert/overt visual pursuit tasks a...

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Autores principales:	Ken-ichi Morishige, Nobuo Hiroe, Masa-aki Sato, Mitsuo Kawato
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4bbd5db87e604c43b3094a9460122c50
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spelling	oai:doaj.org-article:4bbd5db87e604c43b3094a9460122c502021-12-02T16:14:55ZCommon cortical areas have different neural mechanisms for covert and overt visual pursuits10.1038/s41598-021-93259-92045-2322https://doaj.org/article/4bbd5db87e604c43b3094a9460122c502021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93259-9https://doaj.org/toc/2045-2322Abstract Although humans can direct their attention to visual targets with or without eye movements, it remains unclear how different brain mechanisms control visual attention and eye movements together and/or separately. Here, we measured MEG and fMRI data during covert/overt visual pursuit tasks and estimated cortical currents using our previously developed extra-dipole, hierarchical Bayesian method. Then, we predicted the time series of target positions and velocities from the estimated cortical currents of each task using a sparse machine-learning algorithm. The predicted target positions/velocities had high temporal correlations with actual visual target kinetics. Additionally, we investigated the generalization ability of predictive models among three conditions: control, covert, and overt pursuit tasks. When training and testing data were the same tasks, the largest reconstructed accuracies were overt, followed by covert and control, in that order. When training and testing data were selected from different tasks, accuracies were in reverse order. These results are well explained by the assumption that predictive models consist of combinations of three computational brain functions: visual information-processing, maintenance of attention, and eye-movement control. Our results indicate that separate subsets of neurons in the same cortical regions control visual attention and eye movements differently.Ken-ichi MorishigeNobuo HiroeMasa-aki SatoMitsuo KawatoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ken-ichi Morishige Nobuo Hiroe Masa-aki Sato Mitsuo Kawato Common cortical areas have different neural mechanisms for covert and overt visual pursuits
description	Abstract Although humans can direct their attention to visual targets with or without eye movements, it remains unclear how different brain mechanisms control visual attention and eye movements together and/or separately. Here, we measured MEG and fMRI data during covert/overt visual pursuit tasks and estimated cortical currents using our previously developed extra-dipole, hierarchical Bayesian method. Then, we predicted the time series of target positions and velocities from the estimated cortical currents of each task using a sparse machine-learning algorithm. The predicted target positions/velocities had high temporal correlations with actual visual target kinetics. Additionally, we investigated the generalization ability of predictive models among three conditions: control, covert, and overt pursuit tasks. When training and testing data were the same tasks, the largest reconstructed accuracies were overt, followed by covert and control, in that order. When training and testing data were selected from different tasks, accuracies were in reverse order. These results are well explained by the assumption that predictive models consist of combinations of three computational brain functions: visual information-processing, maintenance of attention, and eye-movement control. Our results indicate that separate subsets of neurons in the same cortical regions control visual attention and eye movements differently.
format	article
author	Ken-ichi Morishige Nobuo Hiroe Masa-aki Sato Mitsuo Kawato
author_facet	Ken-ichi Morishige Nobuo Hiroe Masa-aki Sato Mitsuo Kawato
author_sort	Ken-ichi Morishige
title	Common cortical areas have different neural mechanisms for covert and overt visual pursuits
title_short	Common cortical areas have different neural mechanisms for covert and overt visual pursuits
title_full	Common cortical areas have different neural mechanisms for covert and overt visual pursuits
title_fullStr	Common cortical areas have different neural mechanisms for covert and overt visual pursuits
title_full_unstemmed	Common cortical areas have different neural mechanisms for covert and overt visual pursuits
title_sort	common cortical areas have different neural mechanisms for covert and overt visual pursuits
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4bbd5db87e604c43b3094a9460122c50
work_keys_str_mv	AT kenichimorishige commoncorticalareashavedifferentneuralmechanismsforcovertandovertvisualpursuits AT nobuohiroe commoncorticalareashavedifferentneuralmechanismsforcovertandovertvisualpursuits AT masaakisato commoncorticalareashavedifferentneuralmechanismsforcovertandovertvisualpursuits AT mitsuokawato commoncorticalareashavedifferentneuralmechanismsforcovertandovertvisualpursuits
_version_	1718384288425050112

Common cortical areas have different neural mechanisms for covert and overt visual pursuits

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