Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytes

Summary: Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A2 (PLA2)-dependent eicosanoid release plays a key role in this. T-helper (Th) 1-derived cytokines are established activators of phospho...

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Autores principales: Eirini Tsirvouli, Felicity Ashcroft, Berit Johansen, Martin Kuiper
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/4bc0bef92b5a41eba07fd5930063ec08
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