Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults

Pneumococcal disease is one of the most common and severe vaccine-preventable diseases (VPDs). Despite the advances in antimicrobial treatment, pneumococcal disease still remains a global burden and exhibits a high mortality rate among people of all ages worldwide. The immunization program of the pn...

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Autores principales: Nobuhiro Asai, Hiroshige Mikamo
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:4bca337e6edd4a2e8257e2bb4e6325c82021-11-25T18:25:18ZRecent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults10.3390/microorganisms91123422076-2607https://doaj.org/article/4bca337e6edd4a2e8257e2bb4e6325c82021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2607/9/11/2342https://doaj.org/toc/2076-2607Pneumococcal disease is one of the most common and severe vaccine-preventable diseases (VPDs). Despite the advances in antimicrobial treatment, pneumococcal disease still remains a global burden and exhibits a high mortality rate among people of all ages worldwide. The immunization program of the pneumococcal conjugate vaccine (PCV) in children has decreased pneumococcal disease incidence in several countries. However, there are several problems regarding the pneumococcal vaccine, such as indications for immunocompetent persons with underlying medical conditions with a risk of pneumococcal disease, the balance of utility and cost, i.e., cost-effectiveness, vaccine coverage rate, serotype replacement, and adverse events. Especially for individuals aged 19–64 at risk of pneumococcal disease, physicians and vaccine providers should make a rational decision whether the patients should be vaccinated or not, since there is insufficient evidence supporting it. We describe this review regarding topics and problems regarding pneumococcal vaccination from the clinician’s point of view.Nobuhiro AsaiHiroshige MikamoMDPI AGarticlepneumococcal vaccinePCV13PPSV23invasive pneumococcal disease<i>streptococcus pneumonia</i>Biology (General)QH301-705.5ENMicroorganisms, Vol 9, Iss 2342, p 2342 (2021)
institution DOAJ
collection DOAJ
language EN
topic pneumococcal vaccine
PCV13
PPSV23
invasive pneumococcal disease
<i>streptococcus pneumonia</i>
Biology (General)
QH301-705.5
spellingShingle pneumococcal vaccine
PCV13
PPSV23
invasive pneumococcal disease
<i>streptococcus pneumonia</i>
Biology (General)
QH301-705.5
Nobuhiro Asai
Hiroshige Mikamo
Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
description Pneumococcal disease is one of the most common and severe vaccine-preventable diseases (VPDs). Despite the advances in antimicrobial treatment, pneumococcal disease still remains a global burden and exhibits a high mortality rate among people of all ages worldwide. The immunization program of the pneumococcal conjugate vaccine (PCV) in children has decreased pneumococcal disease incidence in several countries. However, there are several problems regarding the pneumococcal vaccine, such as indications for immunocompetent persons with underlying medical conditions with a risk of pneumococcal disease, the balance of utility and cost, i.e., cost-effectiveness, vaccine coverage rate, serotype replacement, and adverse events. Especially for individuals aged 19–64 at risk of pneumococcal disease, physicians and vaccine providers should make a rational decision whether the patients should be vaccinated or not, since there is insufficient evidence supporting it. We describe this review regarding topics and problems regarding pneumococcal vaccination from the clinician’s point of view.
format article
author Nobuhiro Asai
Hiroshige Mikamo
author_facet Nobuhiro Asai
Hiroshige Mikamo
author_sort Nobuhiro Asai
title Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
title_short Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
title_full Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
title_fullStr Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
title_full_unstemmed Recent Topics of Pneumococcal Vaccination: Indication of Pneumococcal Vaccine for Individuals at a Risk of Pneumococcal Disease in Adults
title_sort recent topics of pneumococcal vaccination: indication of pneumococcal vaccine for individuals at a risk of pneumococcal disease in adults
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/4bca337e6edd4a2e8257e2bb4e6325c8
work_keys_str_mv AT nobuhiroasai recenttopicsofpneumococcalvaccinationindicationofpneumococcalvaccineforindividualsatariskofpneumococcaldiseaseinadults
AT hiroshigemikamo recenttopicsofpneumococcalvaccinationindicationofpneumococcalvaccineforindividualsatariskofpneumococcaldiseaseinadults
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