Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis

Background and Objective: In recent years, using of local antibiotic as an adjunctive treatment in periodontitis has been considered. The aim of this study was to survey the local effects of Doxycycline with scaling/root planning in treatment of adult periodontitis. Methods: This experimental study...

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Autores principales:	B Amooian, M Vahdat, AK Moghadam Nia
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2004
Materias:	adult periodontitis local therapy doxycycline Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4bced103ddff486b9e41d6e8c5692cd5
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spelling	oai:doaj.org-article:4bced103ddff486b9e41d6e8c5692cd52021-11-10T09:16:26ZEvaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis1561-41072251-7170https://doaj.org/article/4bced103ddff486b9e41d6e8c5692cd52004-12-01T00:00:00Zhttp://jbums.org/article-1-2721-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: In recent years, using of local antibiotic as an adjunctive treatment in periodontitis has been considered. The aim of this study was to survey the local effects of Doxycycline with scaling/root planning in treatment of adult periodontitis. Methods: This experimental study was accomplished on 5 patients with adult periodontitis. The patients were chosen with at least three pockets with depth of approximately ≥4mm and bleeding in each quadrant. After initial preparation and scaling, the jaws were divided into 3 parts upper right: Receiving Doxycycline gel (Case group), upper left: Receiving base gel (Control group) and lower right: Do not received any gel (Sham group). One, three and six months after beginning the study, all the indices were measured again and finally all data were analyzed by statistical tests. Findings: In this study after 6 months, reduction of pocket depth and clinical attachment level (CAL) in case, control and sham groups were difference. Mean of pocket depth in case group was reduced from 2.3±0.5 mm to 1.5±0.6 mm after 3 months, and 1.9±0.6 mm after 6 months, and in control group from 2.2±0.8 mm to 1.6±0.6 mm after 3 months, and 1.8±0.7 mm after 6 months, these differences for clinical attachment level in buccal side of the teeth in 3 groups were significant (P<0.05). Also, there were differences in bleeding index in 3 groups. As for mobility and plaque index there was not any significant difference between the groups. Conclusion: Totally, the outcome of Doxycycline gel and SRR treatment group was satisfied than the other groups during 6 months, although the effects were not too long.B AmooianM VahdatAK Moghadam NiaBabol University of Medical Sciencesarticleadult periodontitislocal therapydoxycyclineMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 6, Iss 5, Pp 17-23 (2004)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	adult periodontitis local therapy doxycycline Medicine R Medicine (General) R5-920
spellingShingle	adult periodontitis local therapy doxycycline Medicine R Medicine (General) R5-920 B Amooian M Vahdat AK Moghadam Nia Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
description	Background and Objective: In recent years, using of local antibiotic as an adjunctive treatment in periodontitis has been considered. The aim of this study was to survey the local effects of Doxycycline with scaling/root planning in treatment of adult periodontitis. Methods: This experimental study was accomplished on 5 patients with adult periodontitis. The patients were chosen with at least three pockets with depth of approximately ≥4mm and bleeding in each quadrant. After initial preparation and scaling, the jaws were divided into 3 parts upper right: Receiving Doxycycline gel (Case group), upper left: Receiving base gel (Control group) and lower right: Do not received any gel (Sham group). One, three and six months after beginning the study, all the indices were measured again and finally all data were analyzed by statistical tests. Findings: In this study after 6 months, reduction of pocket depth and clinical attachment level (CAL) in case, control and sham groups were difference. Mean of pocket depth in case group was reduced from 2.3±0.5 mm to 1.5±0.6 mm after 3 months, and 1.9±0.6 mm after 6 months, and in control group from 2.2±0.8 mm to 1.6±0.6 mm after 3 months, and 1.8±0.7 mm after 6 months, these differences for clinical attachment level in buccal side of the teeth in 3 groups were significant (P<0.05). Also, there were differences in bleeding index in 3 groups. As for mobility and plaque index there was not any significant difference between the groups. Conclusion: Totally, the outcome of Doxycycline gel and SRR treatment group was satisfied than the other groups during 6 months, although the effects were not too long.
format	article
author	B Amooian M Vahdat AK Moghadam Nia
author_facet	B Amooian M Vahdat AK Moghadam Nia
author_sort	B Amooian
title	Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
title_short	Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
title_full	Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
title_fullStr	Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
title_full_unstemmed	Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis
title_sort	evaluation of clinical effects of local form of doxycycline gel with scaling/root planning (srp) in treatment of adult periodontitis
publisher	Babol University of Medical Sciences
publishDate	2004
url	https://doaj.org/article/4bced103ddff486b9e41d6e8c5692cd5
work_keys_str_mv	AT bamooian evaluationofclinicaleffectsoflocalformofdoxycyclinegelwithscalingrootplanningsrpintreatmentofadultperiodontitis AT mvahdat evaluationofclinicaleffectsoflocalformofdoxycyclinegelwithscalingrootplanningsrpintreatmentofadultperiodontitis AT akmoghadamnia evaluationofclinicaleffectsoflocalformofdoxycyclinegelwithscalingrootplanningsrpintreatmentofadultperiodontitis
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Evaluation of clinical effects of local form of Doxycycline gel with Scaling/root planning (SRP) in treatment of adult periodontitis

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