Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

The origin and nature of rebound HIV-1 virus following antiretroviral therapy (ART) discontinuation still remains unclear. Here, Liu et al. suggest that intact proviral DNA in peripheral blood and lymph node mononuclear cells during ART suppression likely is the source of viral rebound following ART...

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Autores principales:	Po-Ting Liu, Brandon F. Keele, Peter Abbink, Noe B. Mercado, Jinyan Liu, Esther A. Bondzie, Abishek Chandrashekar, Erica N. Borducchi, Joseph Hesselgesser, Michael Mish, Gregory Chin, Elena Bekerman, Romas Geleziunas, Dan H. Barouch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4bcf043d109d4ee280c833a2bd8a8741
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spelling	oai:doaj.org-article:4bcf043d109d4ee280c833a2bd8a87412021-12-02T14:42:47ZOrigin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation10.1038/s41467-020-19254-22041-1723https://doaj.org/article/4bcf043d109d4ee280c833a2bd8a87412020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19254-2https://doaj.org/toc/2041-1723The origin and nature of rebound HIV-1 virus following antiretroviral therapy (ART) discontinuation still remains unclear. Here, Liu et al. suggest that intact proviral DNA in peripheral blood and lymph node mononuclear cells during ART suppression likely is the source of viral rebound following ART discontinuation.Po-Ting LiuBrandon F. KeelePeter AbbinkNoe B. MercadoJinyan LiuEsther A. BondzieAbishek ChandrashekarErica N. BorducchiJoseph HesselgesserMichael MishGregory ChinElena BekermanRomas GeleziunasDan H. BarouchNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Po-Ting Liu Brandon F. Keele Peter Abbink Noe B. Mercado Jinyan Liu Esther A. Bondzie Abishek Chandrashekar Erica N. Borducchi Joseph Hesselgesser Michael Mish Gregory Chin Elena Bekerman Romas Geleziunas Dan H. Barouch Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
description	The origin and nature of rebound HIV-1 virus following antiretroviral therapy (ART) discontinuation still remains unclear. Here, Liu et al. suggest that intact proviral DNA in peripheral blood and lymph node mononuclear cells during ART suppression likely is the source of viral rebound following ART discontinuation.
format	article
author	Po-Ting Liu Brandon F. Keele Peter Abbink Noe B. Mercado Jinyan Liu Esther A. Bondzie Abishek Chandrashekar Erica N. Borducchi Joseph Hesselgesser Michael Mish Gregory Chin Elena Bekerman Romas Geleziunas Dan H. Barouch
author_facet	Po-Ting Liu Brandon F. Keele Peter Abbink Noe B. Mercado Jinyan Liu Esther A. Bondzie Abishek Chandrashekar Erica N. Borducchi Joseph Hesselgesser Michael Mish Gregory Chin Elena Bekerman Romas Geleziunas Dan H. Barouch
author_sort	Po-Ting Liu
title	Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
title_short	Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
title_full	Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
title_fullStr	Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
title_full_unstemmed	Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
title_sort	origin of rebound virus in chronically siv-infected rhesus monkeys following treatment discontinuation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4bcf043d109d4ee280c833a2bd8a8741
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Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

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