A genome-wide portrait of pervasive drug contaminants

Abstract Using a validated yeast chemogenomic platform, we characterized the genome-wide effects of several pharmaceutical contaminants, including three N-nitrosamines (NDMA, NDEA and NMBA), two related compounds (DMF and 4NQO) and several of their metabolites. A collection of 4800 non-essential hom...

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Autores principales: Joseph Uche Ogbede, Guri Giaever, Corey Nislow
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4bd709ce55c34412964c9e590340ba41
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