Epothilone D alters normal growth, viability and microtubule dependent intracellular functions of cortical neurons in vitro

Abstract Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat malignancies to great effect. However, this treatment s...

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Bibliographic Details
Main Authors: J. A. Clark, J. A. Chuckowree, M. S. Dyer, T. C. Dickson, C. A. Blizzard
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/4bdba742d30049b0b11e7bf02dd84e9c
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