Epothilone D alters normal growth, viability and microtubule dependent intracellular functions of cortical neurons in vitro

Abstract Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat malignancies to great effect. However, this treatment s...

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Auteurs principaux: J. A. Clark, J. A. Chuckowree, M. S. Dyer, T. C. Dickson, C. A. Blizzard
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/4bdba742d30049b0b11e7bf02dd84e9c
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