Transduction of inflammation from peripheral immune cells to the hippocampus induces neuronal hyperexcitability mediated by Caspase-1 activation

Background: Recent studies report infiltration of peripheral blood mononuclear cells (PBMCs) into the central nervous system (CNS) in epileptic disorders, suggestive of a potential contribution of PBMC extravasation to the generation of seizures. Nevertheless, the underlying mechanisms involved in P...

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Bibliographic Details
Main Authors: Tarek Shaker, Bidisha Chattopadhyaya, Bénédicte Amilhon, Graziella Di Cristo, Alexander G. Weil
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/4bdea1475d054ca59f21452b9df59894
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