Specific hippocampal representations are linked to generalized cortical representations in memory

Memory representations in cortex and hippocampus are reactivated during sharp-wave ripple (SWR) events. Here, the authors show that, in a familiar environment, this activity preferentially links spatially selective hippocampal cells and task general PFC representations, pointing to a potential neura...

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Autores principales: Jai Y. Yu, Daniel F. Liu, Adrianna Loback, Irene Grossrubatscher, Loren M. Frank
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4be7410531a9465090a1276c5eb6f2e2
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Sumario:Memory representations in cortex and hippocampus are reactivated during sharp-wave ripple (SWR) events. Here, the authors show that, in a familiar environment, this activity preferentially links spatially selective hippocampal cells and task general PFC representations, pointing to a potential neural mechanism for generalization of individual experiences.