Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations
Esophageal squamous cell carcinoma (ESCC) exhibits differences in incidence and survival patterns among races. Here, analysis of Chinese and TCGA ESCC patients reveals that Asian patients exhibit higher TP53, EP300 and NFE2L2 mutational frequencies, and mutated CSMD3 associates with better prognosis...
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Nature Portfolio
2017
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oai:doaj.org-article:4be7e068e4044ea8a4dc723b1e1de8712021-12-02T15:38:44ZComparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations10.1038/s41467-017-01730-x2041-1723https://doaj.org/article/4be7e068e4044ea8a4dc723b1e1de8712017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01730-xhttps://doaj.org/toc/2041-1723Esophageal squamous cell carcinoma (ESCC) exhibits differences in incidence and survival patterns among races. Here, analysis of Chinese and TCGA ESCC patients reveals that Asian patients exhibit higher TP53, EP300 and NFE2L2 mutational frequencies, and mutated CSMD3 associates with better prognosis.Jiaying DengHu ChenDaizhan ZhouJunhua ZhangYun ChenQi LiuDashan AiHanting ZhuLi ChuWenjia RenXiaofei ZhangYi XiaMenghong SunHuiwen ZhangJun LiXinxin PengLiang LiLeng HanHui LinXiujun CaiJiaqing XiangShufeng ChenYihua SunYawei ZhangJie ZhangHaiquan ChenShijian ZhangYi ZhaoYun LiuHan LiangKuaile ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jiaying Deng Hu Chen Daizhan Zhou Junhua Zhang Yun Chen Qi Liu Dashan Ai Hanting Zhu Li Chu Wenjia Ren Xiaofei Zhang Yi Xia Menghong Sun Huiwen Zhang Jun Li Xinxin Peng Liang Li Leng Han Hui Lin Xiujun Cai Jiaqing Xiang Shufeng Chen Yihua Sun Yawei Zhang Jie Zhang Haiquan Chen Shijian Zhang Yi Zhao Yun Liu Han Liang Kuaile Zhao Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| description |
Esophageal squamous cell carcinoma (ESCC) exhibits differences in incidence and survival patterns among races. Here, analysis of Chinese and TCGA ESCC patients reveals that Asian patients exhibit higher TP53, EP300 and NFE2L2 mutational frequencies, and mutated CSMD3 associates with better prognosis. |
| format |
article |
| author |
Jiaying Deng Hu Chen Daizhan Zhou Junhua Zhang Yun Chen Qi Liu Dashan Ai Hanting Zhu Li Chu Wenjia Ren Xiaofei Zhang Yi Xia Menghong Sun Huiwen Zhang Jun Li Xinxin Peng Liang Li Leng Han Hui Lin Xiujun Cai Jiaqing Xiang Shufeng Chen Yihua Sun Yawei Zhang Jie Zhang Haiquan Chen Shijian Zhang Yi Zhao Yun Liu Han Liang Kuaile Zhao |
| author_facet |
Jiaying Deng Hu Chen Daizhan Zhou Junhua Zhang Yun Chen Qi Liu Dashan Ai Hanting Zhu Li Chu Wenjia Ren Xiaofei Zhang Yi Xia Menghong Sun Huiwen Zhang Jun Li Xinxin Peng Liang Li Leng Han Hui Lin Xiujun Cai Jiaqing Xiang Shufeng Chen Yihua Sun Yawei Zhang Jie Zhang Haiquan Chen Shijian Zhang Yi Zhao Yun Liu Han Liang Kuaile Zhao |
| author_sort |
Jiaying Deng |
| title |
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| title_short |
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| title_full |
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| title_fullStr |
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| title_full_unstemmed |
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations |
| title_sort |
comparative genomic analysis of esophageal squamous cell carcinoma between asian and caucasian patient populations |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/4be7e068e4044ea8a4dc723b1e1de871 |
| work_keys_str_mv |
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1718386107801927680 |