SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.

Components of promyelocytic leukaemia (PML) nuclear bodies (ND10) are recruited to sites associated with herpes simplex virus type 1 (HSV-1) genomes soon after they enter the nucleus. This cellular response is linked to intrinsic antiviral resistance and is counteracted by viral regulatory protein I...

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Autores principales: Delphine Cuchet-Lourenço, Chris Boutell, Vera Lukashchuk, Kyle Grant, Amanda Sykes, Jill Murray, Anne Orr, Roger D Everett
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/4beb4b6c3fee4d3b9cba26b8e2ad8b3e
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