Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training
Strength training increases systemic oxygen consumption, causing the excessive generation of reactive oxygen species, which in turn, provokes oxidative stress reactions and cellular processes that induce uterine contraction. The aim of this study was to evaluate the possible protective effect of <...
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oai:doaj.org-article:4bf4898919994252b899798cd7d5218e2021-11-25T18:33:51ZSupplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training10.3390/nu131137632072-6643https://doaj.org/article/4bf4898919994252b899798cd7d5218e2021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3763https://doaj.org/toc/2072-6643Strength training increases systemic oxygen consumption, causing the excessive generation of reactive oxygen species, which in turn, provokes oxidative stress reactions and cellular processes that induce uterine contraction. The aim of this study was to evaluate the possible protective effect of <i>Spirulina platensis</i> (SP), an antioxidant blue algae, on the contractile and relaxation reactivity of rat uterus and the balance of oxidative stress/antioxidant defenses. Female Wistar rats were divided into sedentary (CG), trained (TG), and T + supplemented (TG50, TG100) groups. Reactivity was analyzed by AQCAD, oxidative stress was evaluated by the malondialdehyde (MDA) formation, and the antioxidant capacity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Strength training increased contractile reactivity and decreased the pharmaco-mechanical component of relaxing reactivity in rat uterus. In addition, training decreased oxidation inhibition in the plasma and exercise increased oxidative stress in the uterine tissue; however, supplementation with algae prevented this effect and potentiated the increase in antioxidant capacity. Therefore, this study demonstrated that food supplementation prevents changes in reactivity and oxidative stress induced by strength training in a rat uterus, showing for the first time, that the uterus is a target for this exercise modality and antioxidant supplementation with <i>S. platensis</i> is an alternative means of preventing uterine dysfunction.Paula Benvindo FerreiraAnderson Fellyp Avelino DinizFrancisco Fernandes Lacerda JúniorMaria da Conceição Correia SilvaGlêbia Alexa CardosoAlexandre Sérgio SilvaBagnólia Araújo da SilvaMDPI AGarticle<i>Spirulina platensis</i>physical exerciseuterusoxidative stressmuscle reactivityNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3763, p 3763 (2021) |
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<i>Spirulina platensis</i> physical exercise uterus oxidative stress muscle reactivity Nutrition. Foods and food supply TX341-641 |
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<i>Spirulina platensis</i> physical exercise uterus oxidative stress muscle reactivity Nutrition. Foods and food supply TX341-641 Paula Benvindo Ferreira Anderson Fellyp Avelino Diniz Francisco Fernandes Lacerda Júnior Maria da Conceição Correia Silva Glêbia Alexa Cardoso Alexandre Sérgio Silva Bagnólia Araújo da Silva Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
description |
Strength training increases systemic oxygen consumption, causing the excessive generation of reactive oxygen species, which in turn, provokes oxidative stress reactions and cellular processes that induce uterine contraction. The aim of this study was to evaluate the possible protective effect of <i>Spirulina platensis</i> (SP), an antioxidant blue algae, on the contractile and relaxation reactivity of rat uterus and the balance of oxidative stress/antioxidant defenses. Female Wistar rats were divided into sedentary (CG), trained (TG), and T + supplemented (TG50, TG100) groups. Reactivity was analyzed by AQCAD, oxidative stress was evaluated by the malondialdehyde (MDA) formation, and the antioxidant capacity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Strength training increased contractile reactivity and decreased the pharmaco-mechanical component of relaxing reactivity in rat uterus. In addition, training decreased oxidation inhibition in the plasma and exercise increased oxidative stress in the uterine tissue; however, supplementation with algae prevented this effect and potentiated the increase in antioxidant capacity. Therefore, this study demonstrated that food supplementation prevents changes in reactivity and oxidative stress induced by strength training in a rat uterus, showing for the first time, that the uterus is a target for this exercise modality and antioxidant supplementation with <i>S. platensis</i> is an alternative means of preventing uterine dysfunction. |
format |
article |
author |
Paula Benvindo Ferreira Anderson Fellyp Avelino Diniz Francisco Fernandes Lacerda Júnior Maria da Conceição Correia Silva Glêbia Alexa Cardoso Alexandre Sérgio Silva Bagnólia Araújo da Silva |
author_facet |
Paula Benvindo Ferreira Anderson Fellyp Avelino Diniz Francisco Fernandes Lacerda Júnior Maria da Conceição Correia Silva Glêbia Alexa Cardoso Alexandre Sérgio Silva Bagnólia Araújo da Silva |
author_sort |
Paula Benvindo Ferreira |
title |
Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
title_short |
Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
title_full |
Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
title_fullStr |
Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
title_full_unstemmed |
Supplementation with <i>Spirulina platensis</i> Prevents Uterine Diseases Related to Muscle Reactivity and Oxidative Stress in Rats Undergoing Strength Training |
title_sort |
supplementation with <i>spirulina platensis</i> prevents uterine diseases related to muscle reactivity and oxidative stress in rats undergoing strength training |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/4bf4898919994252b899798cd7d5218e |
work_keys_str_mv |
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