PKCɛ switches Aurora B specificity to exit the abscission checkpoint
The Aurora B abscission checkpoint is activated when DNA is retained in the cleavage furrow on completion of anaphase. Here the authors show that PKCɛ directly phosphorylates Aurora B triggering a switch in Aurora B substrate specificity to elicit Borealin phosphorylation and abscission checkpoint e...
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Autores principales: | Tanya Pike, Nicola Brownlow, Svend Kjaer, Jeremy Carlton, Peter J. Parker |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/4bfd8fc68abe4afca1d2df6a2a1d7ed1 |
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