Single-Cell Integration Analysis of Heterotopic Ossification and Fibrocartilage Developmental Lineage: Endoplasmic Reticulum Stress Effector Xbp1 Transcriptionally Regulates the Notch Signaling Pathway to Mediate Fibrocartilage Differentiation

Single-Cell Integration Analysis of Heterotopic Ossification and Fibrocartilage Developmental Lineage: Endoplasmic Reticulum Stress Effector Xbp1 Transcriptionally Regulates the Notch Signaling Pathway to Mediate Fibrocartilage Differentiation

Introduction. Regeneration of fibrochondrocytes is essential for the healing of the tendon-bone interface (TBI), which is similar to the formation of neurogenic heterotopic ossification (HO). Through single-cell integrative analysis, this study explored the homogeneity of HO cells and fibrochondrocy...

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Autores principales: Yisheng Chen, Yaying Sun, Yuzhen Xu, Wei-Wei Lin, Zhiwen Luo, Zhihua Han, Shaohua Liu, Beijie Qi, Chenyu Sun, Ken Go, x.-R. Kang, Jiwu Chen
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
Materias:
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/4c017bd96d424a318c3835daad062698
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