HEMATOLOGICAL PARAMETERS OF HIV-INFECTED PATIENTS IN PROGRESSING IMMUNE DEFICIENCY

Abstract.  A  comparative  analysis  of  some  immunophysiological  and  hematological  parameters  was performed in a group of HIV-infected patients living in a region of Western Siberia (Russia). The study was performed using laboratory, epidemiological and clinical data, within a time period of 1...

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Autor principal: E. V. Butorov
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/4c1b19a577eb409180ff2028414e8f15
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Sumario:Abstract.  A  comparative  analysis  of  some  immunophysiological  and  hematological  parameters  was performed in a group of HIV-infected patients living in a region of Western Siberia (Russia). The study was performed using laboratory, epidemiological and clinical data, within a time period of 1999 through 2009. The  HIV-infected  persons  were  classified  in  two  study  groups  that  differed  in  rates  of  immunodeficiency progression, with respect to age, duration of HIV-infection, clinical stage of HIV-infection, duration of drug addiction, living terms in the Northern Region, concomitant diseases, as well as timing of immunological and hematological examinations. A significant direct correlation has been revealed between the numbers of CD4-, CD8- lymphocytes, and the levels of total protein and albumin in HIV-infected patients. The study of hematological parameters, as related to progression of immune deficiency, is of mutual medical interest, with respect to general assessment of the patients’ health, like as for clinical and immunological prognosis in HIV infection. (Med. Immunol., 2011, vol. 13, N 1, pp 73-78)