USP35 regulates mitotic progression by modulating the stability of Aurora B
Aurora B kinase is a member of the chromosomal passenger complex, which is an indispensable regulator of mitosis. Here the authors show that the deubiquitinating enzyme USP35 has a role in mitotic progression by inhibiting proteasomal degradation of Aurora B kinase, leading to its activation.
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/4c23d20a9cb94e5ea9e1f1228d63465c |
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