RNA polymerase I–Rrn3 complex at 4.8 Å resolution

RNA polymerase I is the central enzyme that synthesizes ribosomal RNA in eukaryotic cells, and its regulation underlies cell growth. Here the authors present a high-resolution cryo-EM structure of the Pol I-Rrn3 complex that explains how Rrn3 specifically recognizes Pol I to form an initiation compe...

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Autores principales:	Christoph Engel, Jürgen Plitzko, Patrick Cramer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4c2415f021604c658399276e18220a22
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id	oai:doaj.org-article:4c2415f021604c658399276e18220a22
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spelling	oai:doaj.org-article:4c2415f021604c658399276e18220a222021-12-02T16:50:15ZRNA polymerase I–Rrn3 complex at 4.8 Å resolution10.1038/ncomms121292041-1723https://doaj.org/article/4c2415f021604c658399276e18220a222016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12129https://doaj.org/toc/2041-1723RNA polymerase I is the central enzyme that synthesizes ribosomal RNA in eukaryotic cells, and its regulation underlies cell growth. Here the authors present a high-resolution cryo-EM structure of the Pol I-Rrn3 complex that explains how Rrn3 specifically recognizes Pol I to form an initiation competent complex.Christoph EngelJürgen PlitzkoPatrick CramerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-5 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christoph Engel Jürgen Plitzko Patrick Cramer RNA polymerase I–Rrn3 complex at 4.8 Å resolution
description	RNA polymerase I is the central enzyme that synthesizes ribosomal RNA in eukaryotic cells, and its regulation underlies cell growth. Here the authors present a high-resolution cryo-EM structure of the Pol I-Rrn3 complex that explains how Rrn3 specifically recognizes Pol I to form an initiation competent complex.
format	article
author	Christoph Engel Jürgen Plitzko Patrick Cramer
author_facet	Christoph Engel Jürgen Plitzko Patrick Cramer
author_sort	Christoph Engel
title	RNA polymerase I–Rrn3 complex at 4.8 Å resolution
title_short	RNA polymerase I–Rrn3 complex at 4.8 Å resolution
title_full	RNA polymerase I–Rrn3 complex at 4.8 Å resolution
title_fullStr	RNA polymerase I–Rrn3 complex at 4.8 Å resolution
title_full_unstemmed	RNA polymerase I–Rrn3 complex at 4.8 Å resolution
title_sort	rna polymerase i–rrn3 complex at 4.8 å resolution
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4c2415f021604c658399276e18220a22
work_keys_str_mv	AT christophengel rnapolymeraseirrn3complexat48aresolution AT jurgenplitzko rnapolymeraseirrn3complexat48aresolution AT patrickcramer rnapolymeraseirrn3complexat48aresolution
_version_	1718383035448033280

RNA polymerase I–Rrn3 complex at 4.8 Å resolution

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