RNA polymerase I–Rrn3 complex at 4.8 Å resolution

RNA polymerase I is the central enzyme that synthesizes ribosomal RNA in eukaryotic cells, and its regulation underlies cell growth. Here the authors present a high-resolution cryo-EM structure of the Pol I-Rrn3 complex that explains how Rrn3 specifically recognizes Pol I to form an initiation compe...

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Autores principales: Christoph Engel, Jürgen Plitzko, Patrick Cramer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4c2415f021604c658399276e18220a22
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