Analysis of amyloid-like secondary structure in the Cryab-R120G knock-in mouse model of hereditary cataracts by two-dimensional infrared spectroscopy.

αB-crystallin is a small heat shock protein that forms a heterooligomeric complex with αA-crystallin in the ocular lens. It is also widely distributed in tissues throughout the body and has been linked with neurodegenerative diseases such as Alzheimer's, where it is associated with amyloid fibr...

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Autores principales: Ariel M Alperstein, Kathleen S Molnar, Sidney S Dicke, Kieran M Farrell, Leah N Makley, Martin T Zanni, Usha P Andley
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4c2942701ef94b0dad0b814255bade00
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