Ethically utilising COVID-19 host-genomic data

Genetic variants that influence susceptibility to COVID-19 have recently been identified. In this manuscript, we identify and discuss some of the ethical and practical issues raised by these studies. We first outline the ethical case for providing COVID-19 susceptibility testing to healthcare worker...

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Auteurs principaux:	Christopher Gyngell, John Christodoulou, Julian Savulescu
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Genetics QH426-470
Accès en ligne:	https://doaj.org/article/4c2dd9f8c8d34dc29acd7e38c8bb3615
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spelling	oai:doaj.org-article:4c2dd9f8c8d34dc29acd7e38c8bb36152021-12-02T14:36:00ZEthically utilising COVID-19 host-genomic data10.1038/s41525-021-00194-92056-7944https://doaj.org/article/4c2dd9f8c8d34dc29acd7e38c8bb36152021-05-01T00:00:00Zhttps://doi.org/10.1038/s41525-021-00194-9https://doaj.org/toc/2056-7944Genetic variants that influence susceptibility to COVID-19 have recently been identified. In this manuscript, we identify and discuss some of the ethical and practical issues raised by these studies. We first outline the ethical case for providing COVID-19 susceptibility testing to healthcare workers, as well as highlighting risks associated with privacy and discrimination. We then argue that the existence of genetically susceptible individuals has implications for the ethical conduct of COVID-19 human challenge trials. Finally, we discuss the ethical issues that could arise from other COVID-19 host–genome interactions, including the prospect of personalized vaccines.Christopher GyngellJohn ChristodoulouJulian SavulescuNature PortfolioarticleMedicineRGeneticsQH426-470ENnpj Genomic Medicine, Vol 6, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Genetics QH426-470
spellingShingle	Medicine R Genetics QH426-470 Christopher Gyngell John Christodoulou Julian Savulescu Ethically utilising COVID-19 host-genomic data
description	Genetic variants that influence susceptibility to COVID-19 have recently been identified. In this manuscript, we identify and discuss some of the ethical and practical issues raised by these studies. We first outline the ethical case for providing COVID-19 susceptibility testing to healthcare workers, as well as highlighting risks associated with privacy and discrimination. We then argue that the existence of genetically susceptible individuals has implications for the ethical conduct of COVID-19 human challenge trials. Finally, we discuss the ethical issues that could arise from other COVID-19 host–genome interactions, including the prospect of personalized vaccines.
format	article
author	Christopher Gyngell John Christodoulou Julian Savulescu
author_facet	Christopher Gyngell John Christodoulou Julian Savulescu
author_sort	Christopher Gyngell
title	Ethically utilising COVID-19 host-genomic data
title_short	Ethically utilising COVID-19 host-genomic data
title_full	Ethically utilising COVID-19 host-genomic data
title_fullStr	Ethically utilising COVID-19 host-genomic data
title_full_unstemmed	Ethically utilising COVID-19 host-genomic data
title_sort	ethically utilising covid-19 host-genomic data
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4c2dd9f8c8d34dc29acd7e38c8bb3615
work_keys_str_mv	AT christophergyngell ethicallyutilisingcovid19hostgenomicdata AT johnchristodoulou ethicallyutilisingcovid19hostgenomicdata AT juliansavulescu ethicallyutilisingcovid19hostgenomicdata
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Ethically utilising COVID-19 host-genomic data

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