“Gene accordions” cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus

Gene tandem amplifications can drive bacterial evolution. Here, Belikova et al. identify copy number variations of lipoprotein-encoding genes in Staphylococcus aureus clinical isolates, and show that the loci expand and contract during bacterial growth in vitro and in mice, leading to changes in imm...

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Autores principales: Darya Belikova, Angelika Jochim, Jeffrey Power, Matthew T. G. Holden, Simon Heilbronner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4c383d564aab421693bdf9003b5298d4
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