“Gene accordions” cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus
Gene tandem amplifications can drive bacterial evolution. Here, Belikova et al. identify copy number variations of lipoprotein-encoding genes in Staphylococcus aureus clinical isolates, and show that the loci expand and contract during bacterial growth in vitro and in mice, leading to changes in imm...
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Autores principales: | Darya Belikova, Angelika Jochim, Jeffrey Power, Matthew T. G. Holden, Simon Heilbronner |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/4c383d564aab421693bdf9003b5298d4 |
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