Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications
Innovations in nanotechnology have had an immense impact on medicine, such as in drug delivery, tissue engineering, and medical devices that combat different pathogens. The pathogens that may cause biofilm-associated nosocomial diseases are multidrug-resistant (MDR) bacteria, such as <i>Escher...
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oai:doaj.org-article:4c3ba9c79b4d4d68b48010cb16a846692021-11-25T18:14:49ZRecent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications10.3390/ma142269321996-1944https://doaj.org/article/4c3ba9c79b4d4d68b48010cb16a846692021-11-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/22/6932https://doaj.org/toc/1996-1944Innovations in nanotechnology have had an immense impact on medicine, such as in drug delivery, tissue engineering, and medical devices that combat different pathogens. The pathogens that may cause biofilm-associated nosocomial diseases are multidrug-resistant (MDR) bacteria, such as <i>Escherichia coli</i> (<i>E. coli</i>), <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>), <i>Staphylococcus aureus</i> (<i>S. aureus</i>), including both Gram-positive and Gram-negative bacterial species. About 65–80% of infections are caused by biofilm-associated pathogens creating a move in the international community toward developing antimicrobial therapies to eliminate such pathogenic infections. Several nanomaterials (NMs) have been discovered and significantly employed in various antipathogenic therapies. These NMs have unique properties of singlet oxygen production, high absorption of near-infrared irradiation, and reasonable conversion of light to heat. In this review, functionalized NPs that combat different pathogenic infections are introduced. This review highlights NMs that combat infections caused by multidrug-resistant (MDR) and other pathogenic microorganisms. It also highlights the biomedical application of NPs with regard to antipathogenic activities.Shahin Shah KhanIrfan UllahSadeeq UllahRuipeng AnHaijun XuKaili NieChaoyong LiuLuo LiuMDPI AGarticlenanoparticlessurface functionalizationNIRMDRantibacterial activitiesnosocomial diseasesTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6932, p 6932 (2021) |
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nanoparticles surface functionalization NIR MDR antibacterial activities nosocomial diseases Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 |
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nanoparticles surface functionalization NIR MDR antibacterial activities nosocomial diseases Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 Shahin Shah Khan Irfan Ullah Sadeeq Ullah Ruipeng An Haijun Xu Kaili Nie Chaoyong Liu Luo Liu Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
description |
Innovations in nanotechnology have had an immense impact on medicine, such as in drug delivery, tissue engineering, and medical devices that combat different pathogens. The pathogens that may cause biofilm-associated nosocomial diseases are multidrug-resistant (MDR) bacteria, such as <i>Escherichia coli</i> (<i>E. coli</i>), <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>), <i>Staphylococcus aureus</i> (<i>S. aureus</i>), including both Gram-positive and Gram-negative bacterial species. About 65–80% of infections are caused by biofilm-associated pathogens creating a move in the international community toward developing antimicrobial therapies to eliminate such pathogenic infections. Several nanomaterials (NMs) have been discovered and significantly employed in various antipathogenic therapies. These NMs have unique properties of singlet oxygen production, high absorption of near-infrared irradiation, and reasonable conversion of light to heat. In this review, functionalized NPs that combat different pathogenic infections are introduced. This review highlights NMs that combat infections caused by multidrug-resistant (MDR) and other pathogenic microorganisms. It also highlights the biomedical application of NPs with regard to antipathogenic activities. |
format |
article |
author |
Shahin Shah Khan Irfan Ullah Sadeeq Ullah Ruipeng An Haijun Xu Kaili Nie Chaoyong Liu Luo Liu |
author_facet |
Shahin Shah Khan Irfan Ullah Sadeeq Ullah Ruipeng An Haijun Xu Kaili Nie Chaoyong Liu Luo Liu |
author_sort |
Shahin Shah Khan |
title |
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
title_short |
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
title_full |
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
title_fullStr |
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
title_full_unstemmed |
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications |
title_sort |
recent advances in the surface functionalization of nanomaterials for antimicrobial applications |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/4c3ba9c79b4d4d68b48010cb16a84669 |
work_keys_str_mv |
AT shahinshahkhan recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT irfanullah recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT sadeequllah recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT ruipengan recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT haijunxu recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT kailinie recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT chaoyongliu recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications AT luoliu recentadvancesinthesurfacefunctionalizationofnanomaterialsforantimicrobialapplications |
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1718411435491459072 |