Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling

Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling

LUBAC is involved in adding linear ubiquitin chains to important immune signaling proteins. Here the authors show that this mechanism is effective in inhibiting STAT1-mediated interferon signaling, and that the deubiquitinase OTULIN can remove these linear ubiquitins from STAT1 to reactivate this an...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yibo Zuo, Qian Feng, Lincong Jin, Fan Huang, Ying Miao, Jin Liu, Ying Xu, Xiangjie Chen, Hongguang Zhang, Tingting Guo, Yukang Yuan, Liting Zhang, Jun Wang, Hui Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/4c4454e0aa0248c9a214db9c6f0ed420
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares