Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy

Masashi Sakamoto, Ryuya Hashimoto, Izumi Yoshida, Takatoshi Maeno Department of Ophthalmology, Sakura Medical Center of Toho University, Shimoshizu, Sakura, Japan Purpose: We retrospectively reviewed patients with postoperative neovascular glaucoma (NVG) after vitrectomy for proliferative diabetic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sakamoto M, Hashimoto R, Yoshida I, Maeno T
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://doaj.org/article/4c5316525eab408c8eb886237adbdf5a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:4c5316525eab408c8eb886237adbdf5a
record_format dspace
spelling oai:doaj.org-article:4c5316525eab408c8eb886237adbdf5a2021-12-02T01:14:03ZRisk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy1177-5483https://doaj.org/article/4c5316525eab408c8eb886237adbdf5a2018-04-01T00:00:00Zhttps://www.dovepress.com/risk-factors-for-requirement-of-filtration-surgery-after-vitrectomy-in-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Masashi Sakamoto, Ryuya Hashimoto, Izumi Yoshida, Takatoshi Maeno Department of Ophthalmology, Sakura Medical Center of Toho University, Shimoshizu, Sakura, Japan Purpose: We retrospectively reviewed patients with postoperative neovascular glaucoma (NVG) after vitrectomy for proliferative diabetic retinopathy to investigate how variables assessed before, during, and after vitrectomy are associated with the requirement for filtration surgery. Patients and methods: The subjects in this retrospective, observational, comparative study were 55 consecutive patients (61 eyes) who underwent vitrectomy for proliferative diabetic retinopathy at Toho University Sakura Medical Center between December 2011 and November 2016, were followed up for at least 6 months after surgery, and developed NVG within 2 years after surgery. They comprised 44 men and 11 women of mean age 52.4±9.1 years, who were followed up for a mean 7.1±6.1 months. We collected data on the following 16 variables: sex, age, history of panretinal photocoagulation completed within 3 months before vitrectomy, presence/absence of a lens, obvious iris/angle neovascularization, tractional retinal detachment, diabetic macular edema, vitreous hemorrhage, visual acuity and intraocular pressure before vitrectomy and at the onset of NVG, glycated hemoglobin, fasting blood glucose, estimated glomerular filtration rate, and use of intraoperative gas tamponade. Results: Logistic regression analysis with the backward elimination method identified preoperative fasting hyperglycemia (P=0.08), high intraocular pressure at the onset of NVG (P=0.04), and use of gas tamponade during vitrectomy (P=0.008) to be significant risk factors for requirement of filtration surgery. Conclusion: Preoperative fasting hyperglycemia, high intraocular pressure at the onset of NVG, and use of gas tamponade during vitrectomy predispose patients to require filtration surgery in the event of postoperative NVG. Keywords: neovascular glaucoma, proliferative diabetic retinopathy, vitrectomy, gas tamponadeSakamoto MHashimoto RYoshida IMaeno TDove Medical Pressarticleneovascular glaucomaproliferative diabetic retinopathyvitrectomygas tamponadeOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 733-738 (2018)
institution DOAJ
collection DOAJ
language EN
topic neovascular glaucoma
proliferative diabetic retinopathy
vitrectomy
gas tamponade
Ophthalmology
RE1-994
spellingShingle neovascular glaucoma
proliferative diabetic retinopathy
vitrectomy
gas tamponade
Ophthalmology
RE1-994
Sakamoto M
Hashimoto R
Yoshida I
Maeno T
Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
description Masashi Sakamoto, Ryuya Hashimoto, Izumi Yoshida, Takatoshi Maeno Department of Ophthalmology, Sakura Medical Center of Toho University, Shimoshizu, Sakura, Japan Purpose: We retrospectively reviewed patients with postoperative neovascular glaucoma (NVG) after vitrectomy for proliferative diabetic retinopathy to investigate how variables assessed before, during, and after vitrectomy are associated with the requirement for filtration surgery. Patients and methods: The subjects in this retrospective, observational, comparative study were 55 consecutive patients (61 eyes) who underwent vitrectomy for proliferative diabetic retinopathy at Toho University Sakura Medical Center between December 2011 and November 2016, were followed up for at least 6 months after surgery, and developed NVG within 2 years after surgery. They comprised 44 men and 11 women of mean age 52.4±9.1 years, who were followed up for a mean 7.1±6.1 months. We collected data on the following 16 variables: sex, age, history of panretinal photocoagulation completed within 3 months before vitrectomy, presence/absence of a lens, obvious iris/angle neovascularization, tractional retinal detachment, diabetic macular edema, vitreous hemorrhage, visual acuity and intraocular pressure before vitrectomy and at the onset of NVG, glycated hemoglobin, fasting blood glucose, estimated glomerular filtration rate, and use of intraoperative gas tamponade. Results: Logistic regression analysis with the backward elimination method identified preoperative fasting hyperglycemia (P=0.08), high intraocular pressure at the onset of NVG (P=0.04), and use of gas tamponade during vitrectomy (P=0.008) to be significant risk factors for requirement of filtration surgery. Conclusion: Preoperative fasting hyperglycemia, high intraocular pressure at the onset of NVG, and use of gas tamponade during vitrectomy predispose patients to require filtration surgery in the event of postoperative NVG. Keywords: neovascular glaucoma, proliferative diabetic retinopathy, vitrectomy, gas tamponade
format article
author Sakamoto M
Hashimoto R
Yoshida I
Maeno T
author_facet Sakamoto M
Hashimoto R
Yoshida I
Maeno T
author_sort Sakamoto M
title Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
title_short Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
title_full Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
title_fullStr Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
title_full_unstemmed Risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
title_sort risk factors for requirement of filtration surgery after vitrectomy in patients with proliferative diabetic retinopathy
publisher Dove Medical Press
publishDate 2018
url https://doaj.org/article/4c5316525eab408c8eb886237adbdf5a
work_keys_str_mv AT sakamotom riskfactorsforrequirementoffiltrationsurgeryaftervitrectomyinpatientswithproliferativediabeticretinopathy
AT hashimotor riskfactorsforrequirementoffiltrationsurgeryaftervitrectomyinpatientswithproliferativediabeticretinopathy
AT yoshidai riskfactorsforrequirementoffiltrationsurgeryaftervitrectomyinpatientswithproliferativediabeticretinopathy
AT maenot riskfactorsforrequirementoffiltrationsurgeryaftervitrectomyinpatientswithproliferativediabeticretinopathy
_version_ 1718403197625696256