Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring

Junfeng Chen et al. examine potential functional consequences of reproduction timing-associated TSHR alleles segregating in Atlantic herring. By comparing fish that spawn during the spring to those that spawn in the autumn, they find that the spring-allele is correlated with enhanced cAMP signaling...

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Autores principales: Junfeng Chen, Huijuan Bi, Mats E. Pettersson, Daiki X. Sato, Angela P. Fuentes-Pardo, Chunheng Mo, Shady Younis, Ola Wallerman, Patric Jern, Gregorio Molés, Ana Gómez, Gunnar Kleinau, Patrick Scheerer, Leif Andersson
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4c568d32a12445638dba01ae6f0f5cdf
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spelling oai:doaj.org-article:4c568d32a12445638dba01ae6f0f5cdf2021-12-02T17:44:54ZFunctional differences between TSHR alleles associate with variation in spawning season in Atlantic herring10.1038/s42003-021-02307-72399-3642https://doaj.org/article/4c568d32a12445638dba01ae6f0f5cdf2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02307-7https://doaj.org/toc/2399-3642Junfeng Chen et al. examine potential functional consequences of reproduction timing-associated TSHR alleles segregating in Atlantic herring. By comparing fish that spawn during the spring to those that spawn in the autumn, they find that the spring-allele is correlated with enhanced cAMP signaling and that both coding and non-coding variants in the TSHR locus contribute to seasonal reproduction.Junfeng ChenHuijuan BiMats E. PetterssonDaiki X. SatoAngela P. Fuentes-PardoChunheng MoShady YounisOla WallermanPatric JernGregorio MolésAna GómezGunnar KleinauPatrick ScheererLeif AnderssonNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Junfeng Chen
Huijuan Bi
Mats E. Pettersson
Daiki X. Sato
Angela P. Fuentes-Pardo
Chunheng Mo
Shady Younis
Ola Wallerman
Patric Jern
Gregorio Molés
Ana Gómez
Gunnar Kleinau
Patrick Scheerer
Leif Andersson
Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
description Junfeng Chen et al. examine potential functional consequences of reproduction timing-associated TSHR alleles segregating in Atlantic herring. By comparing fish that spawn during the spring to those that spawn in the autumn, they find that the spring-allele is correlated with enhanced cAMP signaling and that both coding and non-coding variants in the TSHR locus contribute to seasonal reproduction.
format article
author Junfeng Chen
Huijuan Bi
Mats E. Pettersson
Daiki X. Sato
Angela P. Fuentes-Pardo
Chunheng Mo
Shady Younis
Ola Wallerman
Patric Jern
Gregorio Molés
Ana Gómez
Gunnar Kleinau
Patrick Scheerer
Leif Andersson
author_facet Junfeng Chen
Huijuan Bi
Mats E. Pettersson
Daiki X. Sato
Angela P. Fuentes-Pardo
Chunheng Mo
Shady Younis
Ola Wallerman
Patric Jern
Gregorio Molés
Ana Gómez
Gunnar Kleinau
Patrick Scheerer
Leif Andersson
author_sort Junfeng Chen
title Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
title_short Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
title_full Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
title_fullStr Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
title_full_unstemmed Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring
title_sort functional differences between tshr alleles associate with variation in spawning season in atlantic herring
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4c568d32a12445638dba01ae6f0f5cdf
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