Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.

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Auteurs principaux:	L. M. Schiffmann, J. P. Werthenbach, F. Heintges-Kleinhofer, J. M. Seeger, M. Fritsch, S. D. Günther, S. Willenborg, S. Brodesser, C. Lucas, C. Jüngst, M. C. Albert, F. Schorn, A. Witt, C. T. Moraes, C. J. Bruns, M. Pasparakis, M. Krönke, S. A. Eming, O. Coutelle, H. Kashkar
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021
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spelling	oai:doaj.org-article:4c6615fd88894f849a3f974b6b81f0212021-12-02T16:18:02ZMitochondrial respiration controls neoangiogenesis during wound healing and tumour growth10.1038/s41467-020-17472-22041-1723https://doaj.org/article/4c6615fd88894f849a3f974b6b81f0212020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17472-2https://doaj.org/toc/2041-1723During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.L. M. SchiffmannJ. P. WerthenbachF. Heintges-KleinhoferJ. M. SeegerM. FritschS. D. GüntherS. WillenborgS. BrodesserC. LucasC. JüngstM. C. AlbertF. SchornA. WittC. T. MoraesC. J. BrunsM. PasparakisM. KrönkeS. A. EmingO. CoutelleH. KashkarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
description	During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.
format	article
author	L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar
author_facet	L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar
author_sort	L. M. Schiffmann
title	Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_short	Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_full	Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_fullStr	Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_full_unstemmed	Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_sort	mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021
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Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

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