Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.

Guardado en:
Detalles Bibliográficos
Autores principales: L. M. Schiffmann, J. P. Werthenbach, F. Heintges-Kleinhofer, J. M. Seeger, M. Fritsch, S. D. Günther, S. Willenborg, S. Brodesser, C. Lucas, C. Jüngst, M. C. Albert, F. Schorn, A. Witt, C. T. Moraes, C. J. Bruns, M. Pasparakis, M. Krönke, S. A. Eming, O. Coutelle, H. Kashkar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:4c6615fd88894f849a3f974b6b81f021
record_format dspace
spelling oai:doaj.org-article:4c6615fd88894f849a3f974b6b81f0212021-12-02T16:18:02ZMitochondrial respiration controls neoangiogenesis during wound healing and tumour growth10.1038/s41467-020-17472-22041-1723https://doaj.org/article/4c6615fd88894f849a3f974b6b81f0212020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17472-2https://doaj.org/toc/2041-1723During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.L. M. SchiffmannJ. P. WerthenbachF. Heintges-KleinhoferJ. M. SeegerM. FritschS. D. GüntherS. WillenborgS. BrodesserC. LucasC. JüngstM. C. AlbertF. SchornA. WittC. T. MoraesC. J. BrunsM. PasparakisM. KrönkeS. A. EmingO. CoutelleH. KashkarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
L. M. Schiffmann
J. P. Werthenbach
F. Heintges-Kleinhofer
J. M. Seeger
M. Fritsch
S. D. Günther
S. Willenborg
S. Brodesser
C. Lucas
C. Jüngst
M. C. Albert
F. Schorn
A. Witt
C. T. Moraes
C. J. Bruns
M. Pasparakis
M. Krönke
S. A. Eming
O. Coutelle
H. Kashkar
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
description During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.
format article
author L. M. Schiffmann
J. P. Werthenbach
F. Heintges-Kleinhofer
J. M. Seeger
M. Fritsch
S. D. Günther
S. Willenborg
S. Brodesser
C. Lucas
C. Jüngst
M. C. Albert
F. Schorn
A. Witt
C. T. Moraes
C. J. Bruns
M. Pasparakis
M. Krönke
S. A. Eming
O. Coutelle
H. Kashkar
author_facet L. M. Schiffmann
J. P. Werthenbach
F. Heintges-Kleinhofer
J. M. Seeger
M. Fritsch
S. D. Günther
S. Willenborg
S. Brodesser
C. Lucas
C. Jüngst
M. C. Albert
F. Schorn
A. Witt
C. T. Moraes
C. J. Bruns
M. Pasparakis
M. Krönke
S. A. Eming
O. Coutelle
H. Kashkar
author_sort L. M. Schiffmann
title Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_short Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_full Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_fullStr Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_full_unstemmed Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
title_sort mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021
work_keys_str_mv AT lmschiffmann mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT jpwerthenbach mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT fheintgeskleinhofer mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT jmseeger mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT mfritsch mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT sdgunther mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT swillenborg mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT sbrodesser mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT clucas mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT cjungst mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT mcalbert mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT fschorn mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT awitt mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT ctmoraes mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT cjbruns mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT mpasparakis mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT mkronke mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT saeming mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT ocoutelle mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
AT hkashkar mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth
_version_ 1718384228326965248