Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:4c6615fd88894f849a3f974b6b81f021 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:4c6615fd88894f849a3f974b6b81f0212021-12-02T16:18:02ZMitochondrial respiration controls neoangiogenesis during wound healing and tumour growth10.1038/s41467-020-17472-22041-1723https://doaj.org/article/4c6615fd88894f849a3f974b6b81f0212020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17472-2https://doaj.org/toc/2041-1723During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.L. M. SchiffmannJ. P. WerthenbachF. Heintges-KleinhoferJ. M. SeegerM. FritschS. D. GüntherS. WillenborgS. BrodesserC. LucasC. JüngstM. C. AlbertF. SchornA. WittC. T. MoraesC. J. BrunsM. PasparakisM. KrönkeS. A. EmingO. CoutelleH. KashkarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
description |
During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair. |
format |
article |
author |
L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar |
author_facet |
L. M. Schiffmann J. P. Werthenbach F. Heintges-Kleinhofer J. M. Seeger M. Fritsch S. D. Günther S. Willenborg S. Brodesser C. Lucas C. Jüngst M. C. Albert F. Schorn A. Witt C. T. Moraes C. J. Bruns M. Pasparakis M. Krönke S. A. Eming O. Coutelle H. Kashkar |
author_sort |
L. M. Schiffmann |
title |
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
title_short |
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
title_full |
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
title_fullStr |
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
title_full_unstemmed |
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
title_sort |
mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/4c6615fd88894f849a3f974b6b81f021 |
work_keys_str_mv |
AT lmschiffmann mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT jpwerthenbach mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT fheintgeskleinhofer mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT jmseeger mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT mfritsch mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT sdgunther mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT swillenborg mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT sbrodesser mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT clucas mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT cjungst mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT mcalbert mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT fschorn mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT awitt mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT ctmoraes mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT cjbruns mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT mpasparakis mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT mkronke mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT saeming mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT ocoutelle mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth AT hkashkar mitochondrialrespirationcontrolsneoangiogenesisduringwoundhealingandtumourgrowth |
_version_ |
1718384228326965248 |