Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease

Crohn’s disease is associated with altered intestinal microbiota. Here, the authors show that the microbe Atopobium parvulumis associated with Crohn’s disease patients, triggers colitis in a mouse model, and that scavenging microbe-induced hydrogen sulfide improved symptoms in mice.

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Autores principales:	Walid Mottawea, Cheng-Kang Chiang, Marcus Mühlbauer, Amanda E. Starr, James Butcher, Turki Abujamel, Shelley A. Deeke, Annette Brandel, Hu Zhou, Shadi Shokralla, Mehrdad Hajibabaei, Ruth Singleton, Eric I. Benchimol, Christian Jobin, David R. Mack, Daniel Figeys, Alain Stintzi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4c6883f1b92a41c686eb0855792ce2fa
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spelling	oai:doaj.org-article:4c6883f1b92a41c686eb0855792ce2fa2021-12-02T14:39:55ZAltered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease10.1038/ncomms134192041-1723https://doaj.org/article/4c6883f1b92a41c686eb0855792ce2fa2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13419https://doaj.org/toc/2041-1723Crohn’s disease is associated with altered intestinal microbiota. Here, the authors show that the microbe Atopobium parvulumis associated with Crohn’s disease patients, triggers colitis in a mouse model, and that scavenging microbe-induced hydrogen sulfide improved symptoms in mice.Walid MottaweaCheng-Kang ChiangMarcus MühlbauerAmanda E. StarrJames ButcherTurki AbujamelShelley A. DeekeAnnette BrandelHu ZhouShadi ShokrallaMehrdad HajibabaeiRuth SingletonEric I. BenchimolChristian JobinDavid R. MackDaniel FigeysAlain StintziNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Walid Mottawea Cheng-Kang Chiang Marcus Mühlbauer Amanda E. Starr James Butcher Turki Abujamel Shelley A. Deeke Annette Brandel Hu Zhou Shadi Shokralla Mehrdad Hajibabaei Ruth Singleton Eric I. Benchimol Christian Jobin David R. Mack Daniel Figeys Alain Stintzi Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
description	Crohn’s disease is associated with altered intestinal microbiota. Here, the authors show that the microbe Atopobium parvulumis associated with Crohn’s disease patients, triggers colitis in a mouse model, and that scavenging microbe-induced hydrogen sulfide improved symptoms in mice.
format	article
author	Walid Mottawea Cheng-Kang Chiang Marcus Mühlbauer Amanda E. Starr James Butcher Turki Abujamel Shelley A. Deeke Annette Brandel Hu Zhou Shadi Shokralla Mehrdad Hajibabaei Ruth Singleton Eric I. Benchimol Christian Jobin David R. Mack Daniel Figeys Alain Stintzi
author_facet	Walid Mottawea Cheng-Kang Chiang Marcus Mühlbauer Amanda E. Starr James Butcher Turki Abujamel Shelley A. Deeke Annette Brandel Hu Zhou Shadi Shokralla Mehrdad Hajibabaei Ruth Singleton Eric I. Benchimol Christian Jobin David R. Mack Daniel Figeys Alain Stintzi
author_sort	Walid Mottawea
title	Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
title_short	Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
title_full	Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
title_fullStr	Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
title_full_unstemmed	Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
title_sort	altered intestinal microbiota–host mitochondria crosstalk in new onset crohn’s disease
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4c6883f1b92a41c686eb0855792ce2fa
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Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease

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