Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus repl...
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Nature Portfolio
2018
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oai:doaj.org-article:4c6b1d50965b47689e1f6421a43712f62021-12-02T17:32:32ZBeclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase10.1038/s41467-018-03658-22041-1723https://doaj.org/article/4c6b1d50965b47689e1f6421a43712f62018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03658-2https://doaj.org/toc/2041-1723Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus replication.Fangfang LiChangwei ZhangYinzi LiGuanwei WuXilin HouXueping ZhouAiming WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
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Science Q Fangfang Li Changwei Zhang Yinzi Li Guanwei Wu Xilin Hou Xueping Zhou Aiming Wang Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
description |
Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus replication. |
format |
article |
author |
Fangfang Li Changwei Zhang Yinzi Li Guanwei Wu Xilin Hou Xueping Zhou Aiming Wang |
author_facet |
Fangfang Li Changwei Zhang Yinzi Li Guanwei Wu Xilin Hou Xueping Zhou Aiming Wang |
author_sort |
Fangfang Li |
title |
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
title_short |
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
title_full |
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
title_fullStr |
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
title_full_unstemmed |
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase |
title_sort |
beclin1 restricts rna virus infection in plants through suppression and degradation of the viral polymerase |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/4c6b1d50965b47689e1f6421a43712f6 |
work_keys_str_mv |
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_version_ |
1718380245786034176 |