Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase

Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus repl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fangfang Li, Changwei Zhang, Yinzi Li, Guanwei Wu, Xilin Hou, Xueping Zhou, Aiming Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/4c6b1d50965b47689e1f6421a43712f6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:4c6b1d50965b47689e1f6421a43712f6
record_format dspace
spelling oai:doaj.org-article:4c6b1d50965b47689e1f6421a43712f62021-12-02T17:32:32ZBeclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase10.1038/s41467-018-03658-22041-1723https://doaj.org/article/4c6b1d50965b47689e1f6421a43712f62018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03658-2https://doaj.org/toc/2041-1723Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus replication.Fangfang LiChangwei ZhangYinzi LiGuanwei WuXilin HouXueping ZhouAiming WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fangfang Li
Changwei Zhang
Yinzi Li
Guanwei Wu
Xilin Hou
Xueping Zhou
Aiming Wang
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
description Plant DNA virus replication is inhibited by autophagy, but the interplay between plant RNA viruses and autophagy is less clear. Here, Li et al. show that turnip mosaic virus infection activates autophagy and that Beclin1, a core autophagy component, binds the viral polymerase and inhibits virus replication.
format article
author Fangfang Li
Changwei Zhang
Yinzi Li
Guanwei Wu
Xilin Hou
Xueping Zhou
Aiming Wang
author_facet Fangfang Li
Changwei Zhang
Yinzi Li
Guanwei Wu
Xilin Hou
Xueping Zhou
Aiming Wang
author_sort Fangfang Li
title Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
title_short Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
title_full Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
title_fullStr Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
title_full_unstemmed Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase
title_sort beclin1 restricts rna virus infection in plants through suppression and degradation of the viral polymerase
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/4c6b1d50965b47689e1f6421a43712f6
work_keys_str_mv AT fangfangli beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT changweizhang beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT yinzili beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT guanweiwu beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT xilinhou beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT xuepingzhou beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
AT aimingwang beclin1restrictsrnavirusinfectioninplantsthroughsuppressionanddegradationoftheviralpolymerase
_version_ 1718380245786034176