Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells.

Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells.

<h4>Background</h4>Sepsis and jaundice are common conditions in newborns that can lead to brain damage. Though lipopolysaccharide (LPS) is known to alter the integrity of the blood-brain barrier (BBB), little is known on the effects of unconjugated bilirubin (UCB) and even less on the jo...

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Autores principales: Filipa L Cardoso, Agnes Kittel, Szilvia Veszelka, Inês Palmela, Andrea Tóth, Dora Brites, Mária A Deli, Maria A Brito
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/4c6be953bd9146c8a9fc12fee2060354
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