The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Resistance or tolerance to traditional antibiotics is a challenging issue in antimicrobial chemotherapy. Moreover, traditional bactericidal antibiotics kill only actively growing bacterial cells, whereas nongrowing metabolically inactive cells are tolerant to and therefore “persist” in the...

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Bibliographic Details
Main Authors: Wooseong Kim, Guijin Zou, Wen Pan, Nico Fricke, Hammad A. Faizi, Soo Min Kim, Rajamohammed Khader, Silei Li, Kiho Lee, Iliana Escorba, Petia M. Vlahovska, Huajian Gao, Frederick M. Ausubel, Eleftherios Mylonakis
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
persisters
antibiotic tolerance
antimicrobial resistance
MRSA
membrane-active antimicrobials
antibiotic
Microbiology
QR1-502
Online Access:https://doaj.org/article/4c6e5367321845828598c4354294512c
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