Mitochondrial DNA copy number, but not haplogroup, confers a genetic susceptibility to leprosy in Han Chinese from Southwest China.
<h4>Background</h4>Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an unculturable pathogen with an exceptionally eroded genome. The high level of inactivation of gene function in M. leprae, including many genes in its metabolic pathways, has led to a dependence o...
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Autores principales: | Dong Wang, Ling-Yan Su, A-Mei Zhang, Yu-Ye Li, Xiao-An Li, Ling-Ling Chen, Heng Long, Yong-Gang Yao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/4c776fc6eefd4c43af0df312445b1c86 |
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