Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis

Abstract Background Our aim was to comprehensively review published evidence on the association between having a congenital heart disease (CHD) compared with not, on educational attainment (i.e. not obtaining a university degree, completing secondary education, or completing any vocational training...

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Autores principales:	Lucia Cocomello, Arnaldo Dimagli, Giovanni Biglino, Rosie Cornish, Massimo Caputo, Deborah A. Lawlor
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Congenital heart disease Educational attainment Systematic review Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/4c8c4fa1667d4d98bf160d971a305151
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spelling	oai:doaj.org-article:4c8c4fa1667d4d98bf160d971a3051512021-11-21T12:04:11ZEducational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis10.1186/s12872-021-02349-z1471-2261https://doaj.org/article/4c8c4fa1667d4d98bf160d971a3051512021-11-01T00:00:00Zhttps://doi.org/10.1186/s12872-021-02349-zhttps://doaj.org/toc/1471-2261Abstract Background Our aim was to comprehensively review published evidence on the association between having a congenital heart disease (CHD) compared with not, on educational attainment (i.e. not obtaining a university degree, completing secondary education, or completing any vocational training vs. obtaining/completing) in adults. Method Studies were eligible if they reported the rate, odds, or proportion of level of educational attainment in adults by whether or not they had a CHD. Result Out of 1537 articles screened, we identified 11 (N = 104,585 participants, 10,487 with CHD), 10 (N = 167,470 participants, 11,820 with CHD), and 8 (N = 150,813 participants, 9817 with CHD) studies reporting information on university education, secondary education, and vocational training, respectively in both CHD and non-CHD participants. Compared to their non-CHD peers, CHD patients were more likely not to obtain a university degree (OR = 1.38, 95% CI [1.16, 1.65]), complete secondary education (OR = 1.33, 95% CI [1.09, 1.61]) or vocational training (OR = 1.11, 95% CI [0.98, 1.26]). For all three outcomes there was evidence of between study heterogeneity, with geographical area contributing to this heterogeneity. Conclusion This systematic review identified all available published data on educational attainment in CHD patients. Despite broad inclusion criteria we identified relatively few studies that included a comparison group from the same population, and amongst those that did, few adjusted for key confounders. Pooled analyses suggest evidence of lower levels of educational attainment in patients with CHD when compared to non-CHD peers. The extent to which this may be explained by confounding factors, such as parental education, or mediated by treatments is not possible to discern from the current research literature.Lucia CocomelloArnaldo DimagliGiovanni BiglinoRosie CornishMassimo CaputoDeborah A. LawlorBMCarticleCongenital heart diseaseEducational attainmentSystematic reviewDiseases of the circulatory (Cardiovascular) systemRC666-701ENBMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Congenital heart disease Educational attainment Systematic review Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Congenital heart disease Educational attainment Systematic review Diseases of the circulatory (Cardiovascular) system RC666-701 Lucia Cocomello Arnaldo Dimagli Giovanni Biglino Rosie Cornish Massimo Caputo Deborah A. Lawlor Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
description	Abstract Background Our aim was to comprehensively review published evidence on the association between having a congenital heart disease (CHD) compared with not, on educational attainment (i.e. not obtaining a university degree, completing secondary education, or completing any vocational training vs. obtaining/completing) in adults. Method Studies were eligible if they reported the rate, odds, or proportion of level of educational attainment in adults by whether or not they had a CHD. Result Out of 1537 articles screened, we identified 11 (N = 104,585 participants, 10,487 with CHD), 10 (N = 167,470 participants, 11,820 with CHD), and 8 (N = 150,813 participants, 9817 with CHD) studies reporting information on university education, secondary education, and vocational training, respectively in both CHD and non-CHD participants. Compared to their non-CHD peers, CHD patients were more likely not to obtain a university degree (OR = 1.38, 95% CI [1.16, 1.65]), complete secondary education (OR = 1.33, 95% CI [1.09, 1.61]) or vocational training (OR = 1.11, 95% CI [0.98, 1.26]). For all three outcomes there was evidence of between study heterogeneity, with geographical area contributing to this heterogeneity. Conclusion This systematic review identified all available published data on educational attainment in CHD patients. Despite broad inclusion criteria we identified relatively few studies that included a comparison group from the same population, and amongst those that did, few adjusted for key confounders. Pooled analyses suggest evidence of lower levels of educational attainment in patients with CHD when compared to non-CHD peers. The extent to which this may be explained by confounding factors, such as parental education, or mediated by treatments is not possible to discern from the current research literature.
format	article
author	Lucia Cocomello Arnaldo Dimagli Giovanni Biglino Rosie Cornish Massimo Caputo Deborah A. Lawlor
author_facet	Lucia Cocomello Arnaldo Dimagli Giovanni Biglino Rosie Cornish Massimo Caputo Deborah A. Lawlor
author_sort	Lucia Cocomello
title	Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
title_short	Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
title_full	Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
title_fullStr	Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
title_full_unstemmed	Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
title_sort	educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis
publisher	BMC
publishDate	2021
url	https://doaj.org/article/4c8c4fa1667d4d98bf160d971a305151
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Educational attainment in patients with congenital heart disease: a comprehensive systematic review and meta-analysis

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