Expanding the genome-targeting scope and the site selectivity of high-precision base editors
Base editors can be limited by precision and the size of the target window. Here the authors test Cas9s that recognise alternative PAMs to obtain a series of high-precision editors.
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Autores principales: | Junjie Tan, Fei Zhang, Daniel Karcher, Ralph Bock |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/4c8e2d4fc82f41ffb4aaddcc178d1e0f |
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