Mutations in the C-terminus of HBoV NS1 affect the function of NP1

Abstract Human bocavirus 1 (HBoV1) is an autonomous parvovirus in the Bocaparvovirus genus. The multifunctional nuclear protein NP1 is involved in viral replication. In the present study, we found that the mutations in the C-terminus of NS1 affected NP1 function in viral replication. Knocking out NP...

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Autores principales: Junmei Zhang, Yan Bai, Bing Zhu, Sujuan Hao, Zhen Chen, Hanzhong Wang, Wuxiang Guan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4c9ae7e602524ea99bc6368ba0148dc2
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